GABA - Molecular Devices
GABA - Molecular Devices
GABA - Molecular Devices
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PatchXpress assays - detection of BDZ site agonistsEC 50= 31 6 nM (n = 7)Control current amplitudes240220(number of cells shown in brackets)Percentage increase in <strong>GABA</strong> response20018016014012010080604020Current (nA)2.52.01.51.00.5(7)(7)01E-4 1E-3 0.01 0.1 1[cf EC 50= 40nM, Rabe et.al. 2007][Diazepam] M0.01 M <strong>GABA</strong> 1 M DiazepamMean amplitudes of EC20 <strong>GABA</strong> andhighest concentration of diazepam
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