GABA - Molecular Devices

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GABAa 1 Ionworks assayA) Analysis of GABA-induced current amplitudeSingle cell (HT)PPC (Quattro)B) Concentration-response curves for GABAHTPPC

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GABAa 1 Ionworks assayA) Analysis of GABA-induced current amplitudeSingle cell (HT)PPC (Quattro)B) Concentration-response curves for GABAHTPPC

Comparison of Ionworks and PatchXpress data–GABA A 1 vs. 3IonWorks Quattro (n = 3) PatchXpress (n = 6-15)IW EC 50PX EC 50Published EC 50Reference 3.6 µM 4.8 µM 2.1 µM Williams & Akabas, 2000 9.6 µM 11.4 µM 15 µM Smith et.al. 2001

Page 6 and 7: PatchXpress assays - protocol for B
Page 8 and 9: PatchXpress assays - protocol for B
Page 10 and 11: Use of Ionworks for ligand-gated ch
Page 14 and 15: Ionworks assays - detection of GABA
Page 16 and 17: Ionworks assays - detection of subt
Page 18 and 19: Summary and Conclusions• Electrop

GABA - Molecular Devices

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