Download Pharmacy Curriculum Draft (NCRC); 2011
Download Pharmacy Curriculum Draft (NCRC); 2011 Download Pharmacy Curriculum Draft (NCRC); 2011
GENERAL PROPERTIES, CHEMISTRY BIOLOGICALACTION,STRUCTURE ACTIVITY RELATIONSHIP ANDTHERAPEUTICAPPLICATIONS OF THE FOLLOWING:i. Sulphonamides: Prontosil, sulphanilamide, Sulphapyridine,sulphadimidine, Sulfamethoxazole, Sulfadiazine and Sulfafurazole.ii. Antimalarials: 4-Aminoquinolines, 8-Aminoquinolines, 9-Amino acridines,Biguanides, Pyrimidine analogues, Mefloquine and Cinchoha alkaloids.iii. Diuretics: Mercaptomerin, Meralluride, Thiazides, Sprironolac-tone,Theophylline, Furosemide, Acetazolamide, Ethacrynic acid and Triameterene.iv. Antitubercular Drugs: Ethambutol, Isonicotinic acid, Hydrazid, Rifampacin,Thioguanine, Pyrazinamide, cycloserine, Ethunamide, Cytarabine, 5-Flourouracil and Dacarbazine.v. Antiviral Drugs: Acyclovir, Tromantadine Hydrochloride and Ribavirin.vi. Immunosuppressant Agents: Azathioprine and Cyclosporin.vii. Antibiotics:Penicillins, Cephalosporins, Streptomycin, Chloramphenicol,Tetracyclines, Kanamycin and Erythromycin.PHARM 729 PHARMACEUTICAL CHEMISTRY-VI (Medicinal Chemistry-II)[Lab.]Cr. Hr.: 01 Marks: 50NOTE:- Practical of the subject shall be designed from time to time on the basis of theabove mentioned theoretical topics and availability of the facilities, e.g.Estimation of functional groups; Carboxylic, Hydroxy, Amino and Nitrogroups; Determination of Molecular weights of Organic Compounds. Synthesisof Paracetamol, Salicylic Acid, Methyl salicylate, Azobenzene, Benzoic Acid, 5-Hydroxy-1, 3-benzoxazol-2-one, Aspirin, P-nitrosophenol, 3-nitrophthalic acid,o-Chloro-benzoic acid. Assay of the Drugs like Sulpha drugs, Aspirin,Paracetamol, Benzyl Penicillin. Inorganic Preparations.(Note: A minimum of 10 practicals will be conducted)Recommended Books:1. Martin and Cook, Remington Practice of Pharmaceutical Science, 12 thEd,Mack Publishing Company, USA, 20012. Foye W O, Principles of Medicinal Chemistry, 6 th Ed, Verghese PublisingHouse, Bomby, 2008.3. Tyagi, Textbook of Synthetic Drugs, Anmol Publications, Delhi, 1990.4. Alferd Burger, Medicinal Chemistry, 6 th Ed, Jhon Willey & Sons, New York,2003.5. Block, Roche, Soine and Wilson, Inorganic and Medicinal PharmaceuticalChemistry, Verghese Publishing House, Bombay, 1986.90 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
6. Block, Roche, Soine and Wilson. Inorganic and Medicinal PharmaceuticalChemistry, Lee & Febiger, Philadelphia, USA, 1983.-----------------------------------------------------------------------------------------------------------NOTE: Upon completion of recognized Pharm. D. degree, a pharmacy graduateis required to undergo residency based training for a period of 1 year inany area; at general or private Hospital, pharmaceutical industry,community pharmacy, marketing, research & development and publichealth recognized by the Pharmacy Council of Pakistan. The objective ofthe residency is to undergo a planned training on aspects of pharmacypractice under the supervision of a registered pharmacist. After passingthe Pharmacy examination and completing 1 year of residency, graduatesare eligible to register with the Pharmacy Council and may practice as aregistered pharmacist in Pakistan.FACULTY OF PHARMACYThe faculty will comprise of the following departments with relevant subjects1. Department of Pharmaceutics• Pharmaceutics-I (Physical Pharmacy)• Pharmaceutics-II (Dosage Forms Science)• Pharmaceutics-III (Pharmaceutical Microbiology & immunology)• Pharmaceutics-IV(Industrial Pharmacy)• Pharmaceutics-V (Biopharmaceutics)• Pharmaceutics-VI (Pharmaceutical Quality Management)• Pharmaceutics-VII (Pharmaceutical Technology)2. Department of Pharmaceutical Chemistry• Pharmaceutical Chemistry-I (Organic Chemistry)• Pharmaceutical Chemistry-II (Biochemistry)• Pharmaceutical Chemistry-III (Pharmaceutical Analysis)• Pharmaceutical Chemistry-IV (Medicinal Chemistry)3. Department of Pharmacognosy• Pharmacognosy-I• Pharmacognosy-II4. Department of Pharmacology• Physiology• Anatomy & Histology• Pathology91 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
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GENERAL PROPERTIES, CHEMISTRY BIOLOGICALACTION,STRUCTURE ACTIVITY RELATIONSHIP ANDTHERAPEUTICAPPLICATIONS OF THE FOLLOWING:i. Sulphonamides: Prontosil, sulphanilamide, Sulphapyridine,sulphadimidine, Sulfamethoxazole, Sulfadiazine and Sulfafurazole.ii. Antimalarials: 4-Aminoquinolines, 8-Aminoquinolines, 9-Amino acridines,Biguanides, Pyrimidine analogues, Mefloquine and Cinchoha alkaloids.iii. Diuretics: Mercaptomerin, Meralluride, Thiazides, Sprironolac-tone,Theophylline, Furosemide, Acetazolamide, Ethacrynic acid and Triameterene.iv. Antitubercular Drugs: Ethambutol, Isonicotinic acid, Hydrazid, Rifampacin,Thioguanine, Pyrazinamide, cycloserine, Ethunamide, Cytarabine, 5-Flourouracil and Dacarbazine.v. Antiviral Drugs: Acyclovir, Tromantadine Hydrochloride and Ribavirin.vi. Immunosuppressant Agents: Azathioprine and Cyclosporin.vii. Antibiotics:Penicillins, Cephalosporins, Streptomycin, Chloramphenicol,Tetracyclines, Kanamycin and Erythromycin.PHARM 729 PHARMACEUTICAL CHEMISTRY-VI (Medicinal Chemistry-II)[Lab.]Cr. Hr.: 01 Marks: 50NOTE:- Practical of the subject shall be designed from time to time on the basis of theabove mentioned theoretical topics and availability of the facilities, e.g.Estimation of functional groups; Carboxylic, Hydroxy, Amino and Nitrogroups; Determination of Molecular weights of Organic Compounds. Synthesisof Paracetamol, Salicylic Acid, Methyl salicylate, Azobenzene, Benzoic Acid, 5-Hydroxy-1, 3-benzoxazol-2-one, Aspirin, P-nitrosophenol, 3-nitrophthalic acid,o-Chloro-benzoic acid. Assay of the Drugs like Sulpha drugs, Aspirin,Paracetamol, Benzyl Penicillin. Inorganic Preparations.(Note: A minimum of 10 practicals will be conducted)Recommended Books:1. Martin and Cook, Remington Practice of Pharmaceutical Science, 12 thEd,Mack Publishing Company, USA, 20012. Foye W O, Principles of Medicinal Chemistry, 6 th Ed, Verghese PublisingHouse, Bomby, 2008.3. Tyagi, Textbook of Synthetic Drugs, Anmol Publications, Delhi, 1990.4. Alferd Burger, Medicinal Chemistry, 6 th Ed, Jhon Willey & Sons, New York,2003.5. Block, Roche, Soine and Wilson, Inorganic and Medicinal PharmaceuticalChemistry, Verghese Publishing House, Bombay, 1986.90 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,