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1. Leon Shargel, Applied Pharmacokinetics and Biopharmaceutics,Appleton & Lange, New York, 5th Ed., 2008.2. Malcoln Rouland, Thomous N Tozer, Clinical Pharmacokinetics, William& Willkins, London, 1995.3. Milo Gibaldi, Biopharmaceutics and Clinical Pharmacokinetics, 4 thEd,Marchel& Dakker Inc, New York, 2008.4. Gibbson and Skett, Introduction to Drug Metabolism, 3 rd Ed,Champ &Hall, London, 2001.5. Robert E Notari, Biopharmaceutics and Clinical Pharmacokinetics, 4 thEd, Marchel & Dakker Inc, New York, 1988.6. Sarfraz Niazi, Text Book of Biopharmaceutics & ClinicalPharmacokinetics. Appleton-Century-Crofts, New York, 1985.7. Gul Majid Khan,Biopharmaceutics: Text Book for <strong>Pharmacy</strong> Students &Working Pharmacists[ISBN978-969-9101-00-7]8. Gul Majid Khan,Text Book of Biopharmaceutics & Pharmacokinetics forPost Graduate Students9. Gul Majid Khan,Laboratory Manual of Biopharmaceutics&Pharmacokinetics[ISBN 978-969-9101-02-1]10. Stephen H Curry, Drug disposition and pharmacokinetics, Black WellScientific Publishing, Oxford, 1983.11. Avraham Yacobi, Toxicokinetics and New Drug Development, ParamountPress, New York, 1989.12. P Macheras, C Reppas and J B Dressman, Biopharmaceutics of orally13. administered drugs, Ellis Horwood Limited, London (1995).14. Albert P Li, In vitro approaches for evaluation of drug efficacyandtoxicity, CRC Press LLC USA, 2004.15. Ronald D Schoenwald, Pharmacokinetics in drug discovery andDevelopment, CRC Press LLC, USA, 2002.PHARM 628 PHARMACEUTICS-XII (Pharmaceutical QualityManagement-II) [Th.]Cr. Hr.: 03 Marks: 1001. BIOLOGICAL ASSAYS: Biological methods, Standard preparations andunits of activity, Bioassay of antibiotics, Bioassay of insulin injection, Assayof prepared digitalis and Assay of Vitamin D.2. ALCOHOL DETERMINATION:Alcoholometric methods, Problemduring distillation of alcohol, Method for liquids containing less than 30% ormore than 30% alcohol and special treatment before distillation.3. ALKALOIDAL DRUG ASSAY: Weighing for assay, Extraction of drugs,Maceration, Percolation, Continuous extraction, Purification of Alkaloids anddetermination of alkaloids.4. QUALITY ASSURANCE OF VACCINES: Introduction, Quality measuresfor stability of vaccines, potency testing, post market surveillance of78 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
vaccines.5. MISCELLANEOUS DETERMINATIONS AND TESTS:Determination ofweight/ml, Water/Moisture content, Loss on Drying, Evaluation of Ointments,Ash contents and Alkalinity of Glass.6. STATISTICAL INTERPRETATION OF QUALITYCONTROLCHARTS DURING MANUFACTURING PROCESSES.PHARM 629 PHARMACEUTICS-XII (Pharmaceutical QualityManagement-II) [Lab.]Cr. Hr.: 01 Marks: 50NOTE:-Practical of the subject shall be designed from time to time on the basis of theabove mentioned theoretical topics and availability of the facilities, e.g.Assay of various spirits, tinctures, extracts, syrups and elixirs, Assay ofOintments and suppositories, Assay of tablets and capsules, Test foralkalinity of glass, Determination of alcohol contents in thePharmaceutical preparations and Pyrogen test. Sterility test,Determination of Ash contents, Determination of Moisture contents,Determination of total solids, Determination of viscosity of syrups, gels,etc., Determination of emulsion types.(Note: A minimum of 10 practical will be performed)Recommended Books:1. A H Beckett and J B Stennlake, Practical Pharmaceutical Chemistry, Part-I andII. The Alton Press, London. 2001.2. A M Knevel and F E Digangi, Jenkin’s Quantitative Pharmaceutical Chemistry,McGraw-Hill Book Company, New York. 1977.3. K A Connors, A Text Book of Pharmaceutical Analysis, 3 rd Ed, John-Wiley andSons, New York. 1999.4. A Braithwaite and F J Smith, Chromatographic Methods, Chapman and Hall,London. 1995.5. G D Christian, Analytical Chemistry, John Wiley and Sons, New York. 2003.6. Karamt A Javaid, Pharmaceutical Quality Assurance in Class, Industry andMarket, Aziz Publishers, Lahore-Pakistan (1993).7. Gil Bismuth and Shosh Neumann, Cleaning Validation, A practicalapproach.CRC Press, LLC, USA, 2003.8. J T Carstersen and C T Rhodes, Drug Stability: Principles and Practices, 3rdedition (revised and expanded) Mercel Dekker, New York. 2000.9. Sydney H Willig, Good Manufacturing Practices for Pharmaceuticals. 5 th Ed,Marcel Dekker Publishing.2000.10. Bryant R, The pharmaceutical Quality Control Hand Book, Aster PublishingCorporation, Eugene, 1989.11. Braun R E,Introduction to Instrumental Analysis, McGraw-Hill Book Co, NY,1987.79 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
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NATIONAL CURRICULUM REVISIONCOMMITT
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The aims and objectives of Doctor o
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14. To prepare pharmacy graduates f
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and its Applications in Pharmacy)[L
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DETAILS OF COURSES ( SEMESTER SYSTE
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PHARM 311 PHARMACEUTICS-I (Physical
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9. Naser-ud-Din, Introduction to St
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Expression of Genetic Information,
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2. STRUCTURE OF CELL: Cell Membrane
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Communications SkillsObjectives: En
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Experiments to demonstrate some of
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1990.9. Naser-ud-Din, Introduction
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Page 53 and 54: 5. Plant SteroidsIntroduction, extr
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Page 59 and 60: of frog. To demonstrate the effects
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Page 63 and 64: • Components of a Computer• Com
Page 65 and 66: 1. INTRODUCTION(a) Role of Pharmaci
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Page 95 and 96: Paper 4 Pharmacy Practice -VI (Fore
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Page 99 and 100: c. Proteins and Amino acids: Brief
Page 101 and 102: 3. PHYSICO-CHEMICAL PRINCIPLES:a. S
Page 103 and 104: 2. Cooper and Gunns Tutorial Pharma
Page 105 and 106: Experiences, Motivation and Emotion
Page 107 and 108: 5. CENTRAL NERVOUS SYSTEM: Nerve Mu
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Page 111 and 112: 1. DESCRIPTION OF STATISTICS: Descr
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Page 115 and 116: 1. Writing. Advanced by Ron White.
Page 117 and 118: effervescent, granulated salts. Har
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Page 127 and 128: Objectives• Develop vision of his
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2 To enhance understanding of the s
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1) Basic Concepts of Islam & Scienc
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Chondroma, Fibroma, Leomyoma, Neofi
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Note:(a)(b)(c)(d)Pollution and its
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14. Pharmacology by Ran & Dell, 6 t
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(e) Phenolic volatile oils: Clove,
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their identification. Isolation and
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6. ROLE OF PHARMACIST: As Public He
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d. I.R. Spectroscopye. Mass Spectro
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F O U R T H P R O F E S S I O N A L
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16. NUCLEAR PHARMACY.17. THE PHYSIC
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I. Ensure continuity of pharmaceuti
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1. MASS TRANSFER.2. HEAT TRANSFER.3
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Delhi, 1986.4. Remington’s Pharma
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14. IN-VITRO-IN-VIVO CORRELATION (I
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5. QUALITY CONTROL OF STERILE PRODU
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F I N A L P R O F E S S I O N A LPH
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3. Tyagi, Textbook of Synthetic Dru
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Horwood Publishing limited, West Su
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NOTE:- Practical of the subject sha
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3. The Pharmacy Act 1967.4. The Poi
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5. Application of Computers in Hosp
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