hydride reduction and wolf krishnner reduction friedel craft’s reaction,Perkin reaction, Cannizzaro reaction. Mannich Reaction3. REACTIVE INTERMEDIATES AND FREE RADICALS: Introduction,Generation, stability and Reaction of the following intermediates:Carbocations, Carbanions, Carbenes, Nitrenes,Benzynes, Type ofreactions:An Overview. Free radicals, Free radical scavengers and theirapplications.4. CARBONIUM ION REARRANGEMENTS: Pinacol-Pinacolone, wigner-Meerwein, Wolf, Hofmann and Beckmann rearrangements.5. CARBANIONS: Condensation reaction (Aldol condensation Favorskiirearrangement; writing reaction)PHARM 323 PHARMACEUTICAL CHEMISTRY-II (ORGANIC-I)[Lab.]Cr. Hr.: 01 Marks: 50NOTE: - Practicals of the subject shall be designed from time to time on the basis ofthe above mentioned theoretical topics and availability of the facilities, e.g.OrganicPreparations: Benzoic acid, Aspirin, Acetanilide, Iodoform, Nitrophenol, 3-nitrophthalic acid, Benzhydrol and 2,4-Dinitrochlorobenzene.Recommended Books:1. Peter Sykes, A guide Book to Mechanism in Organic Chemistry,Longman, New York, 6 th Ed, 1991.2. E L Eliel, Stereochemistry of Carbon Compounds, Tata McGraw- Hill,New Delhi, 1992.3. Rehman and M Younis, Organic Chemistry for B.Sc. students, IlmiKitab Khana, Lahore, 1997.4. L Finar, Organic Chemistry Vol I, Person Education Asia, 6th Ed., NewDelhi, 2001.5. Raj K Bansel, Organic Reaction Mechanism, Tata McGraw-Hill, NewDelhi, 1992.6. Furaiss Brian, Practical Organic Chemistry, 5th Ed., ELBS, London.7. Sykes A P, Guide Book to Mechanism in Organic Chemistry, 6th Ed.,Lonsmen Co, UK, 2008.8. Roberts J D and Caserio M C, Basic Principles of organic Chemistry,24 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
1990.9. Naser-ud-Din, Introduction to Stereochemistry, Ghafoor StationeryMart, Peshawar, 1994.10. Bhal B S, Textbook of Organic Chemistry, S Chand & Co, New Delhi,16 th Ed., 2007.11. L.G. Wade, Organic Chemistry, Prentice Hall, New York, U.S.A., 7 thEd., 2010.PHARM 324 PHARMACEUTICAL BIO-CHEMISTRY-II [Th.]Cr. Hr.: 03 Marks: 1001. METABOLIC FATE OF BIOMOLECULES (Anabolism and Catabolism):a. Carbohydrates: Introduction to metabolism, Brief introduction to the digestionand absorption of carbohydrates, Aerobic and anaerobic breakdown of Glucose,Glycolysis, Pentose Phosphate Pathway, Glycogenolysis, Glycogenesis,Gluconeogenesis, Citric acid cycle, Energetics of various metabolic processes.b. Lipids: Brief introduction to the digestion and absorption of lipids, Oxidation offatty acids through b-oxidation, Biosynthesis of fatty acids, neutral lipids andcholesterol.c. Proteins and Amino acids: Brief introduction to the digestion and absorption ofproteins and amino acids, Metabolism of essential and non-essential aminoacids, Biosynthesis and catabolism of Haemins and porphyrin compounds.d. Bioenergetics: Principles of bioenergetics. Electron transport chain andoxidative phosphorylation.2. REGULATION OF METABOLIC PROCESSESa. Role of Vitamins: Physiological role of Fat-soluble (A, D, E and K) andWater-soluble (Thiamin, Riboflavin, Pantothenic acid, Niacin, Pyridoxalphosphate, Biotin, Folic acid, Cyanocobalamin- members of B-complex familyand Ascorbic acid), Coenzymes and their role in the regulation of metabolicprocesses.b. Receptor mediated regulation (Hormones): Mechanism of action of hormones,Physiological roles of various hormones, Site of synthesis and target sites ofhormones.c. Secondary Messengers: Role of cAMP, Calcium ions and phosphoinositol in theregulation of metabolic processes.d. Gene Expression: Replication, Transcription and Translation (Gene expression)Introduction to Biotechnology and Genetic Engineering, Basic principles ofRecombinant DNA technology, Pharmaceutical applications, Balance ofCatabolic, Anabolic and Amphibolic processes in human metabolism, Acid-Base and Electrolyte Balance in Human body.3. INTRODUCTION TO CLINICAL CHEMISTRY:Introduction and Importanceof25 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
- Page 1 and 2: NATIONAL CURRICULUM REVISIONCOMMITT
- Page 5 and 6: The aims and objectives of Doctor o
- Page 7 and 8: 14. To prepare pharmacy graduates f
- Page 9 and 10: and its Applications in Pharmacy)[L
- Page 11 and 12: DETAILS OF COURSES ( SEMESTER SYSTE
- Page 13 and 14: PHARM 311 PHARMACEUTICS-I (Physical
- Page 15 and 16: 9. Naser-ud-Din, Introduction to St
- Page 17 and 18: Expression of Genetic Information,
- Page 19 and 20: 2. STRUCTURE OF CELL: Cell Membrane
- Page 21 and 22: Communications SkillsObjectives: En
- Page 23: Experiments to demonstrate some of
- Page 27 and 28: Hemorrhage and Other Causes of Hypo
- Page 29 and 30: IS 402ISLAMIC STUDIESCr. Hr.: 01 Ma
- Page 31 and 32: Publications New Delhi (1989)9) Dr.
- Page 33 and 34: PHARM 413 PHARMACEUTICS-V (Pharmace
- Page 35 and 36: e. Drug treatment of chronic inflam
- Page 37 and 38: j. Labiatae Peppermint, Thyme, Spea
- Page 39 and 40: SECOND SEMESTERPS 403PAKISTAN STUDI
- Page 41 and 42: NOTE:- Practicals of the subject sh
- Page 43 and 44: i. Drugs used for cough (Anti-tussi
- Page 45 and 46: 1. Drugs of Animal OriginGeneral in
- Page 47 and 48: Frequency Table, Diagrams, Pictogra
- Page 49 and 50: pharmaceutical students Churchill L
- Page 51 and 52: anaesthetic drugs on human and the
- Page 53 and 54: 5. Plant SteroidsIntroduction, extr
- Page 55 and 56: Adenoma, Chondroma, Fibroma, Leomyo
- Page 57 and 58: Aluminium Hydroxide, Ammonium Chlor
- Page 59 and 60: of frog. To demonstrate the effects
- Page 61 and 62: 6. Tumor Inhibitors from PlantsIntr
- Page 63 and 64: • Components of a Computer• Com
- Page 65 and 66: 1. INTRODUCTION(a) Role of Pharmaci
- Page 67 and 68: withdrawal, Detection, Management o
- Page 69 and 70: (Note: A minimum of 10 practicals w
- Page 71 and 72: 14. Ronald D Schoenwald, Pharmacoki
- Page 73 and 74: Distribution, Relationship between
- Page 75 and 76:
4. A J Winfield, Pharmaceutical Pra
- Page 77 and 78:
. Factors: persistent, accumulation
- Page 79 and 80:
vaccines.5. MISCELLANEOUS DETERMINA
- Page 81 and 82:
3. T V Ramabhadran, Pharmaceutical
- Page 83 and 84:
1. R Z Hussain, The Manual of Drug
- Page 85 and 86:
NOTE:- Practical of the subject sha
- Page 87 and 88:
PHARM 722 PHARMACY PRACTICE-XIII (C
- Page 89 and 90:
3. The Pharmacy Act 1967.4. The Poi
- Page 91 and 92:
6. Block, Roche, Soine and Wilson.
- Page 93 and 94:
PHARM-D FIVE-YEAR COURSESCHEME OF S
- Page 95 and 96:
Paper 4 Pharmacy Practice -VI (Fore
- Page 97 and 98:
9. PREPARATION AND PROPERTIES OF HE
- Page 99 and 100:
c. Proteins and Amino acids: Brief
- Page 101 and 102:
3. PHYSICO-CHEMICAL PRINCIPLES:a. S
- Page 103 and 104:
2. Cooper and Gunns Tutorial Pharma
- Page 105 and 106:
Experiences, Motivation and Emotion
- Page 107 and 108:
5. CENTRAL NERVOUS SYSTEM: Nerve Mu
- Page 109 and 110:
(b)Spinal Cord — Meninges (C.S.F.
- Page 111 and 112:
1. DESCRIPTION OF STATISTICS: Descr
- Page 113 and 114:
Part: B, (Communications Skills)Obj
- Page 115 and 116:
1. Writing. Advanced by Ron White.
- Page 117 and 118:
effervescent, granulated salts. Har
- Page 119 and 120:
Parasympathetic antagonists.f. Gang
- Page 121 and 122:
(Note: A minimum of 20 practicals w
- Page 123 and 124:
Sources, structure, preparation, de
- Page 125 and 126:
Microbiology with special reference
- Page 127 and 128:
Objectives• Develop vision of his
- Page 129 and 130:
2 To enhance understanding of the s
- Page 131 and 132:
1) Basic Concepts of Islam & Scienc
- Page 133 and 134:
Chondroma, Fibroma, Leomyoma, Neofi
- Page 135 and 136:
Note:(a)(b)(c)(d)Pollution and its
- Page 137 and 138:
14. Pharmacology by Ran & Dell, 6 t
- Page 139 and 140:
(e) Phenolic volatile oils: Clove,
- Page 141 and 142:
their identification. Isolation and
- Page 143 and 144:
6. ROLE OF PHARMACIST: As Public He
- Page 145 and 146:
d. I.R. Spectroscopye. Mass Spectro
- Page 147 and 148:
F O U R T H P R O F E S S I O N A L
- Page 149 and 150:
16. NUCLEAR PHARMACY.17. THE PHYSIC
- Page 151 and 152:
I. Ensure continuity of pharmaceuti
- Page 153 and 154:
1. MASS TRANSFER.2. HEAT TRANSFER.3
- Page 155 and 156:
Delhi, 1986.4. Remington’s Pharma
- Page 157 and 158:
14. IN-VITRO-IN-VIVO CORRELATION (I
- Page 159 and 160:
5. QUALITY CONTROL OF STERILE PRODU
- Page 161 and 162:
F I N A L P R O F E S S I O N A LPH
- Page 163 and 164:
3. Tyagi, Textbook of Synthetic Dru
- Page 165 and 166:
Horwood Publishing limited, West Su
- Page 167 and 168:
NOTE:- Practical of the subject sha
- Page 169 and 170:
3. The Pharmacy Act 1967.4. The Poi
- Page 171 and 172:
5. Application of Computers in Hosp
- Page 173:
RecommendationsAll members of NCRC