Download Pharmacy Curriculum Draft (NCRC); 2011

10. Stephen H Curry, Drug disposition and pharmacokinetics, Black WellScientific Publishing, Oxford, 1983.11. Avraham Yacobi, Toxicokinetics and New Drug Development, ParamountPress, New York, 1989.12. P Macheras, C Reppas and J B Dressman, Biopharmaceutics of orallyadministered drugs, Ellis Horwood Limited, London (1995).13. Albert P Li, In vitro approaches for evaluation of drug efficacy andtoxicity, CRC Press LLC USA, 2004.14. Ronald D Schoenwald, Pharmacokinetics in drug discovery andDevelopment, CRC Press LLC, USA, 2002.PHARMACEUTICS-VI (PHARMACEUTICAL QUALITY MANAGEMENT)(WRITTEN)Paper 5100 Marks1. INTRODUCTION:Basic concepts about introduction of pharmaceutical industry in relevance toquality control departments, testing, quality management system, qualityassurance, Good Manufacturing Practices and Current Good ManufacturingPractices.General understanding of good laboratory practices and validation2. QUALITY CONTROL OF SOLID DOSAGE FORMS (conventional andmodified release dosage forms:(a) Physical tests: Hardness, Thickness and Diameter, Friability,Disintegration, Weight Variation.(b)Chemical tests: Content uniformity, Assay of active ingredients.3. QUALITY CONTROL OF SYRUPS, ELIXIRS, AND DISPERSESYSTEM:Viscosity, its determination and application in the QualityControl of Pharmaceuticals, Weight per ml and Assay of activeingredients.4. QUALITY CONTROL OF SUPPOSITORIES: Disintegration test,Uniformity of weight, Assay of active ingredients, Liquefaction time test andBreaking test.158 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,