demonstrate the graded Dose-Response curve of Acetylcholine on Rabbitintestine. To identify unknown concentration of Acetycholine from gradedDose-Response curves. To demonstrate the general anesthetic effect onrabbits. To demonstrate the effect of sedatives and hypnotics on rabbits. Todemonstrate the anti-nociceptive (nalagesic) effect on mice. To demonstrateantidepressant effect in rats (forced swimming test, tail suspension testYohimbin lethality test).(Note: A minimum of 20 practicals should be conducted)Recommended Books1. Goodman Gilman, Pharmacological basis of therapeutics. 11 th Ed,McGraw-Hill Book Company, New York, 2008.2. Winguard and Brody, Human Pharmacology, Mosby Year Book, Boston, 1991.3. James M Ritter and Lionel De Levis, A Text book of Clinical Pharmacology,5 th Ed, Oxford University Press, New York, 2008.4. R S Satorkar and S D Bhandarkar, Pharmacology and Pharmacotherapeutics,Popular Prakashan, Bomby, 1998.5. J D Tripathy, Essential of Medical Pharmacology, Japees Brother, New Delhi,6th Ed, 2008.6. D R Laurance, Clinical Pharmacology, ELBS, London, 8th Ed., 1998.7. Katzung B G, Basic and Clinical Pharmacology, McGraw-Hill MedicalPublishers, New York, 11th Ed., 2009.8. Lippincott, Pharmacology, 4th Ed, Lippincott Williams & Wilkins, USA,2008.9. Manuchair Edabi, Pharmacology, Little Brown & Company, London, 1993.10. Prof Dr A Qayum, Fundamentals of Experimental Pharmacology.11. Bertram G K,Basic and Clinical Pharmacology, Paramount Publishing Business& Professional Group, USA, 6th Ed., 1995.12. William F Ganong, W F, Review of Medical physiology, 22 nd Ed, 2005PrenticeHall International Inc, New Jersey.13. Qayum A, Fundamentals of Experimental Pharmacology. GhandharaUniversity, Peshawar, 2004.136 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
14. Pharmacology by Ran & Dell, 6 th edition.PHARMACOGNOSY-II (ADVANCED) (WRITTEN)Paper 3100 Marks1. Separation and Isolation of Plant ConstituentsIntroduction and use of spectroscopic and chromatographic techniques for theidentification of natural products. Description and interpretation of ultraviolet,infra-red, mass, nuclear magnetic resonance ( 1 H-NMR and 13 C-NMR) spectra andother advance techniques to elucidate the structure of natural products.2. Carbohydrates and Related CompoundsIntroduction and classification of carbohydrates, sugars as adjuvant in drugs, roleof impurities in sugar substances.(a) Sucrose and Sucrose containing drugs: Sucrose, Dextrose, Liquid glucose,Fructose, Lactose, Xylose, Caramel, Starch, Inulin, Dextrine etc.(b)(c)Cellulose and Cellulose Derivatives: Powdered cellulose, Microcrystallinecellulose, Methyl cellulose, Sodium Carboxy-methyl cellulose.Gums and Mucilage: Tragacanth, Acacia, Sodium Alginate, Agar, Pectin.3. AlkaloidsIntroduction, Properties, Cassification, Function of alkaloids in plants, Methodsof extraction and identification tests.(a) Pyridine — Piperidine Alkaloids: Areca nut, Lobelia.(b) Tropane Alkaloids: Belladonna, Hyoscyamus, Stramonium.(c) Quinoline Alkaloids: Cinchona.(d) Isoquinoline Alkaloids: Ipecacuanha, Opium.(e) Indole alkaloids: Rauwolfia, catharanthus, nux vomica, physostigma, ergot.(f) Imidazole alkaloids: Pilocarpus.(g) Steroidal alkaloids: Veratrum.(h) Alkaloidal amines: Ephedra, colchicum.(i) Purine Bases: Tea, Coffee.137 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
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NATIONAL CURRICULUM REVISIONCOMMITT
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Hemorrhage and Other Causes of Hypo
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pharmaceutical students Churchill L
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