Paper Code: BPL-308Pharmacology-III (Pharmacology-III)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives:The teaching of Pharmacology is aimed at different aspects of drugs <strong>and</strong> pharmaceuticalsused in different diseases. The therapeutic/pharmacological group of drugs is taughtaccording to the classification of World Health Organization. The students are able to knowthe relationship between drug concentration <strong>and</strong> biological response, drug action overtime,factors affecting absorption, distribution, binding, metabolism <strong>and</strong> elimination of chemicals,structure activity relationship, biological changes that result from repeated drug use,tolerance, addiction <strong>and</strong> adverse effects. Process of drug interaction with cellularmacromolecules to alter physiological function <strong>and</strong> site of action including knowledge aboutproper selection of drugs is also covered.UNIT IGeneral Pharmacology: Introduction to Pharmacology, Sources of drugs, Dosageforms <strong>and</strong> routes of administration, mechanism of action, Combined effect of drugs,Factors modifying Drug action, tolerance <strong>and</strong> dependence, Pharmacogenetics.Principles of Basic <strong>and</strong> Clinical Pharmacokinetics: Adverse Drug Reactions <strong>and</strong>treatment of poisoning, ADME drug interactions, Bioassay of Drugs <strong>and</strong> BiologicalSt<strong>and</strong>ardization, Discovery <strong>and</strong> development of new drugs.UNIT II: Pharmacology of Peripheral Nervous System: Neurohumoral transmission (autonomic <strong>and</strong> Somatic). Parasympathomimetics, Parasympatholytics, Sympathomimetics, AdrenergicReceptor <strong>and</strong> neuron blocking agents, Ganglionic, stimulants <strong>and</strong> blocking agents. Neuromuscular blocking Agents.UNIT III: Autocoids: Histamine, 5- HT <strong>and</strong> their antagonists. Prostagl<strong>and</strong>ins, thromboxanes <strong>and</strong> leukotrienes. Pentagastrin, Cholecystokinin, Angiotensin, Bradykinin <strong>and</strong> Substance P. Analgesics, Antipyretics, Anti-inflammatory <strong>and</strong> Anti-gout drugs.UNIT IV: Drugs Acting on the Respiratory System:Anti-asthmatic drugs.Anti-tussives <strong>and</strong> expectorants.Respiratory stimulants.98
Note: Instruction for Examiner:The Semester examination in each theory subject shall be of 50 marks. The examiner will setnine questions. Student will attempt five questions. First question would be of short answertype question covering all four Units (2.5 Marks per Unit) & it would be compulsory. Twoquestions will be set from each unit & out of which c<strong>and</strong>idate will attempt one question. EachQuestion shall be of 10 marks.Suggested Readings (Latest Editions):1. H. P. Rang <strong>and</strong> M M Dale, “Pharmacology”, New York: Churchill Livingstone.2. F. S. K. Berar, “Textbook of Experimental Pharmacology”, New Delhi: Interprint.3. Goodman <strong>and</strong> Gilman’s, “The Pharmacological Basis of Therapeutics”, NewYork: Pregman Press.4. L. Paul, “Principles of Pharmacology”, New York: Chapman <strong>and</strong> Hall.5. B. G. Katzung, “Basic <strong>and</strong> Clinical Pharmacology”, New York: Prentice HallInternational.99
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BPS Mahila Vishwavidyalaya, Khanpur
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7.2 The examination in each semeste
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10. Promotion:11. Division:WhereCi
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16. General Guidelines:16.1 Where t
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Drug chargesPre-packagingCentral st
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Note: Instruction for Examiner:The
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Autonomic nervous system: Physiolog
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Paper Code: BPL-107 REMEDIAL BIOLOG
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Paper Code: BPP-113Pharmaceutical C
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Paper Code: BPP-117REMEDIAL BIOLOGY
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products i.e. PVP, Dextran, absorba
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Suggested Readings (Latest Editions
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Note: Instruction for Examiner:The
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Note: Instruction for Examiner:The
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Paper Code: BPP-112 Pharmaceutical
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Paper Code: BPP-116 Pharmaceutical
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