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Ordinance and Syllabus - Bhagat Phool Singh Mahila ...

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Paper Code: BPL-308Pharmacology-III (Pharmacology-III)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives:The teaching of Pharmacology is aimed at different aspects of drugs <strong>and</strong> pharmaceuticalsused in different diseases. The therapeutic/pharmacological group of drugs is taughtaccording to the classification of World Health Organization. The students are able to knowthe relationship between drug concentration <strong>and</strong> biological response, drug action overtime,factors affecting absorption, distribution, binding, metabolism <strong>and</strong> elimination of chemicals,structure activity relationship, biological changes that result from repeated drug use,tolerance, addiction <strong>and</strong> adverse effects. Process of drug interaction with cellularmacromolecules to alter physiological function <strong>and</strong> site of action including knowledge aboutproper selection of drugs is also covered.UNIT IGeneral Pharmacology: Introduction to Pharmacology, Sources of drugs, Dosageforms <strong>and</strong> routes of administration, mechanism of action, Combined effect of drugs,Factors modifying Drug action, tolerance <strong>and</strong> dependence, Pharmacogenetics.Principles of Basic <strong>and</strong> Clinical Pharmacokinetics: Adverse Drug Reactions <strong>and</strong>treatment of poisoning, ADME drug interactions, Bioassay of Drugs <strong>and</strong> BiologicalSt<strong>and</strong>ardization, Discovery <strong>and</strong> development of new drugs.UNIT II: Pharmacology of Peripheral Nervous System: Neurohumoral transmission (autonomic <strong>and</strong> Somatic). Parasympathomimetics, Parasympatholytics, Sympathomimetics, AdrenergicReceptor <strong>and</strong> neuron blocking agents, Ganglionic, stimulants <strong>and</strong> blocking agents. Neuromuscular blocking Agents.UNIT III: Autocoids: Histamine, 5- HT <strong>and</strong> their antagonists. Prostagl<strong>and</strong>ins, thromboxanes <strong>and</strong> leukotrienes. Pentagastrin, Cholecystokinin, Angiotensin, Bradykinin <strong>and</strong> Substance P. Analgesics, Antipyretics, Anti-inflammatory <strong>and</strong> Anti-gout drugs.UNIT IV: Drugs Acting on the Respiratory System:Anti-asthmatic drugs.Anti-tussives <strong>and</strong> expectorants.Respiratory stimulants.98

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