Paper Code: BPL-304Pharmaceutics-VIII (Dosage Form Design)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives:The objective of the paper is to instill skills among students for designing various dosageforms. Design of dosage form is important in achieving predictable therapeutic response to adrug included in a drug delivery system, which is subjected to large-scale manufacture. Thereproducibility of a product should not differ with its quality <strong>and</strong> efficacy. The studyencompasses formulation aspects with variety of additives available in context with release ofa drug from the drug delivery system.UNIT IPreformulation studies: Study of physical properties of drug like physical form,particle size, shape, density, wetting dielectric constant, solubility, dissolution <strong>and</strong>organoleptic properties <strong>and</strong> their effect on formulation, stability <strong>and</strong> bioavailability.Study of chemical properties of drugs: Study of chemical properties of drugs likehydrolysis, oxidation, reduction, racemisation, polymerization etc. <strong>and</strong> their influenceon formulation <strong>and</strong> stability of products.UNIT II Study of prodrugs: Study of prodrugs in solving problems related to stability,bioavailability <strong>and</strong> elegancy of formulation. Radiopharmaceuticals: Fundamentals of radio pharmacy, therapeutic applicationsof isotopes, diagnostic applications of isotopes, use of radioisotopes in basic research,product development, product production, process control <strong>and</strong> quality control.UNIT III Liquid formulations: Formulation <strong>and</strong> industrial production of liquid <strong>and</strong> semi-solidformulation like suspension, syrup, emulsions <strong>and</strong> ointments. Skin: Structure <strong>and</strong> physiology, physiology of sweating, physiology of skin secretionsformulations, preparations for skin of face <strong>and</strong> h<strong>and</strong>s, formulation, preparation <strong>and</strong>evaluation of cleansing creams, cold creams, cleansing lotions, foundation creams,moisturizing creams, skin tonics, h<strong>and</strong>y <strong>and</strong> body lotion.UNIT IVHairs: Structure <strong>and</strong> functions, formulation, preparation <strong>and</strong> evaluation of shampoos,d<strong>and</strong>ruff preparation, hair creams, <strong>and</strong> fixers, hair colorants, hair remover(depilatories), shaving sticks <strong>and</strong> after shave lotion.Lipsticks: Formulation, preparation <strong>and</strong> evaluation of lipsticks.Formulation, preparation <strong>and</strong> evaluation of other cosmetics like nail lacquers, antiperspirants<strong>and</strong> deodorants, tooth powders <strong>and</strong> tooth paste.94
Note: Instruction for Examiner:The Semester examination in each theory subject shall be of 50 marks. The examiner will setnine questions. Student will attempt five questions. First question would be of short answertype question covering all four Units (2.5 Marks per Unit) & it would be compulsory. Twoquestions will be set from each unit & out of which c<strong>and</strong>idate will attempt one question. EachQuestion shall be of 10 marks.Suggested Readings (Latest Editions):1. H.C. Ansel, “Introduction to Pharmaceutical Dosage Forms <strong>and</strong> Drug DeliverySystems”, Mumbai: K M Varghese& Co.2. Remingtons , “Practice of Pharmacy”, Philadelphia: Lippincott Williams & Wilkins.3. Shah, “SOP”, New Delhi: Business Horizons.4. Banker <strong>and</strong> Rhodes, “Modern Pharmaceutics”, New York: Marcel Dekker5. Swarbrick, “Encyclopedia of Pharmaceutical Technology”, New York : M. Dekker6. “Pharmacopoeia of India”, Govt. of India, Ministry of Health.7. Leon Lachman, H. A. Liberman <strong>and</strong> J. L. Kanig, “The Theory <strong>and</strong> Practice ofIndustrial Pharmacy”, Philadelphia: Lea & Febiger.8. K.A. Connores, G.L. Amiden <strong>and</strong> V.J.Stella, “Chemical stability of Pharmaceuticals”,New York: Wiley & Sons.9. A. Owunwonne, “H<strong>and</strong> Book of Radiopharmaceuticals”, New Delhi: NarosaPublishing House.10. H. S. Bean, A. H. Beckett <strong>and</strong> J. E. Carless, “Advance in Pharmaceutical Sciences”,London: Academic Press.11. Sanju N<strong>and</strong>a, Arun N<strong>and</strong>a <strong>and</strong> Roop K. Khar, “Cosmetic Technology”, Delhi: BirlaPublications Pvt. Ltd.95
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Autonomic nervous system: Physiolog
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Paper Code: BPP-117REMEDIAL BIOLOGY
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products i.e. PVP, Dextran, absorba
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Note: Instruction for Examiner:The
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Note: Instruction for Examiner:The
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