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Ordinance and Syllabus - Bhagat Phool Singh Mahila ...

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Paper Code: BPL-304Pharmaceutics-VIII (Dosage Form Design)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives:The objective of the paper is to instill skills among students for designing various dosageforms. Design of dosage form is important in achieving predictable therapeutic response to adrug included in a drug delivery system, which is subjected to large-scale manufacture. Thereproducibility of a product should not differ with its quality <strong>and</strong> efficacy. The studyencompasses formulation aspects with variety of additives available in context with release ofa drug from the drug delivery system.UNIT IPreformulation studies: Study of physical properties of drug like physical form,particle size, shape, density, wetting dielectric constant, solubility, dissolution <strong>and</strong>organoleptic properties <strong>and</strong> their effect on formulation, stability <strong>and</strong> bioavailability.Study of chemical properties of drugs: Study of chemical properties of drugs likehydrolysis, oxidation, reduction, racemisation, polymerization etc. <strong>and</strong> their influenceon formulation <strong>and</strong> stability of products.UNIT II Study of prodrugs: Study of prodrugs in solving problems related to stability,bioavailability <strong>and</strong> elegancy of formulation. Radiopharmaceuticals: Fundamentals of radio pharmacy, therapeutic applicationsof isotopes, diagnostic applications of isotopes, use of radioisotopes in basic research,product development, product production, process control <strong>and</strong> quality control.UNIT III Liquid formulations: Formulation <strong>and</strong> industrial production of liquid <strong>and</strong> semi-solidformulation like suspension, syrup, emulsions <strong>and</strong> ointments. Skin: Structure <strong>and</strong> physiology, physiology of sweating, physiology of skin secretionsformulations, preparations for skin of face <strong>and</strong> h<strong>and</strong>s, formulation, preparation <strong>and</strong>evaluation of cleansing creams, cold creams, cleansing lotions, foundation creams,moisturizing creams, skin tonics, h<strong>and</strong>y <strong>and</strong> body lotion.UNIT IVHairs: Structure <strong>and</strong> functions, formulation, preparation <strong>and</strong> evaluation of shampoos,d<strong>and</strong>ruff preparation, hair creams, <strong>and</strong> fixers, hair colorants, hair remover(depilatories), shaving sticks <strong>and</strong> after shave lotion.Lipsticks: Formulation, preparation <strong>and</strong> evaluation of lipsticks.Formulation, preparation <strong>and</strong> evaluation of other cosmetics like nail lacquers, antiperspirants<strong>and</strong> deodorants, tooth powders <strong>and</strong> tooth paste.94

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