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Ordinance and Syllabus - Bhagat Phool Singh Mahila ...

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Paper Code: BPL-307Pharmacology-II (Pathophysiology of Common Diseases)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives: The teaching of Pharmacology is aimed at different aspects of drugs <strong>and</strong>pharmaceuticals used in different diseases. The therapeutic/pharmacological group of drugs istaught according to the classification of World Health Organization. The students are able toknow the relationship between drug concentration <strong>and</strong> biological response, drug actionovertime, factors affecting absorption, distribution, binding, metabolism <strong>and</strong> elimination ofchemicals, structure activity relationship, biological changes that result from repeated druguse, tolerance, addiction <strong>and</strong> adverse effects. Process of drug interaction with cellularmacromolecules to alter physiological function <strong>and</strong> site of action including knowledge aboutproper selection of drugs is also covered.UNIT IBasic Principles of Cell Injury <strong>and</strong> Adaptation: Causes of Cellular injury,pathogenesis, <strong>and</strong> morphology of cell injury. Intercellular alterations in lipids,proteins <strong>and</strong> carbohydrates, Cellular adaptation, atrophy, hypertrophy.Basic Mechanisms involved in the process of inflammation <strong>and</strong> repair:Alterations in vascular permeability <strong>and</strong> blood flow, migration of WBCs, acute <strong>and</strong>chronic inflammation, mediators of inflammation, brief outline of the process ofrepair.UNIT II Pathophysiology of following Common Diseases: Alzheimer’s disease, epilepsy,psychosis, depression, mania, hypertension, angina, congestive heart failure,atherosclerosis, myocardial infarction, diabetes.UNIT IIIWherever applicable the molecular basis should be discussed. Pathophysiology of following Common Diseases: Rheumatoid arthritis, gout, Pepticulcer, asthma, ulcerative colitis, various types of Hepatitis, liver cirrhosis, acute <strong>and</strong>chronic renal failure.UNIT IVWherever applicable the molecular basis should be discussed. Pathophysiology of following Common Diseases:Tuberculosis, urinary tractinfections, sexually transmitted diseases, AIDS, anemia, iatrogenic diseases, <strong>and</strong>common types of neoplasm.Wherever applicable the molecular basis should be discussed.81

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