Ordinance and Syllabus - Bhagat Phool Singh Mahila ...
Ordinance and Syllabus - Bhagat Phool Singh Mahila ...
Ordinance and Syllabus - Bhagat Phool Singh Mahila ...
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Paper Code: BPL-305Pharmaceutics-VII (Physical Pharmacy)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives: This subject gives main emphasis on various physical phenomena thatexist behind the formulation of different dosage forms.UNIT IMicromeretics <strong>and</strong> Powder Rheology: Particle size <strong>and</strong> distribution, averageparticle size, number <strong>and</strong> weight distribution, particle number, method of determiningparticle volume, optical microscopy, sieving, sedimentation, measurement, particleshape, specific surface, methods of determining surface area, permeability,adsorption, derived properties of powders, porosity, packing arrangement, densities,bulkiness <strong>and</strong> flow properties.Matter- State <strong>and</strong> selected properties: State of matter, change in the state of matter,latent heats <strong>and</strong> vapour pressure, sublimation-critical point, eutectic mixtures, relativehumidity, liquid complexes, liquid crystals, glassy state, solid-crystalline <strong>and</strong>amorphous polymorphism.UNIT IISurface <strong>and</strong> Interfacial Phenomenon: Liquid interface, surface <strong>and</strong> interfacialtensions, surface free energy measurement of surface <strong>and</strong> interfacial tensions,spreading coefficient, adsorption at liquid interfaces, surface active agents, HLBclassification, solubilization, detergency, electric properties of interface.Viscosity <strong>and</strong> Rheology: Newtonian systems, laws of flow, kinematic viscosity,effect of temperature, non Newtonian systems, pseudoplastic, dilatent, plastic,thixotropy, thixotropy in formulation, determination of viscosity, capillary, fallingball, rotational viscometers.UNIT III Dispersion system: Colloidal dispersions: Definition, types, properties of colloids,protective colloids, applications of colloid in pharmacy. Suspensions <strong>and</strong> Emulsions: Interfacial properties of suspended particles, settling insuspensions, theory of sedimentation, effect of Brownian movement, sedimentationof flocculated particles, sedimentation parameters, wetting of particles, controlledflocculation, flocculation in structured vehicles, rheological considerations,emulsions; types, theories <strong>and</strong> physical stability. Complexation: Classification of complexes, method of preparation <strong>and</strong> analysis,application.79