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Ordinance and Syllabus - Bhagat Phool Singh Mahila ...

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Paper Code: BPL-303 Pharmaceutics-VI (Pharmaceutical Engineering- II)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives: By studying this subject, the students are able to underst<strong>and</strong> that howdifferent dosage forms at large scale are manufactured. This subject also deals with thevarious techniques that involved in development, commercialization <strong>and</strong> manufacturing ofcomponents within the pharmaceuticals industry.UNIT IDistillation: Raoult's law, volatility, boiling point diagrams, azeotropic mixtures,equilibrium diagrams, types of distillation, rectification, rectifying columns,downcomers, material <strong>and</strong> energy balance of a rectifying column, reflux ratio,determination of number of theory plates, H.E.T.P. <strong>and</strong> steam distillation.Extraction: Factors affecting, equipment for extraction of solids i.e. fixed beddiffusion battery, continuous diffusion battery, basket extractor, Rotocel extractor <strong>and</strong>Dorr agitator; equipment for liquid-liquid extraction i.e. extraction towers <strong>and</strong>Podbielniak extractor.UNIT IIMixing: Definition, objectives, mechanism, uniformity index, factors influencingselection of suitable mixer. Study of equipment employed for solid-solid, liquid-liquid<strong>and</strong> solid-liquid mixing. Emulsification equipment.Size separation: Screening equipment i.e. trammels, rotex <strong>and</strong> hummer; airsuspension methods i.e. air separator <strong>and</strong> cyclone separators; hydraulic separation i.e.elutriation <strong>and</strong> double cone emulsifier.UNIT IIICrystallization: Crystal forms, habit, Mier's super saturation theory, crystallizersbased on super saturation, by cooling (i.e. tank crystallizers, agitated batchcrystallizers <strong>and</strong> Swenson-Walker), adiabatic cooling (i.e. vacuum crystallizers) <strong>and</strong>evaporation (i.e. Krystal crystallizers). Material <strong>and</strong> energy balance of crystallizer.Transportation of materials:Liquids: Pumps i.e. airlift, ejector, piston plunger, egg, diaphragm, gear, screw,centrifugal <strong>and</strong> self-priming.Gases: Ejectors, compressors, fans <strong>and</strong> blowers.Solids: InTermittent <strong>and</strong> continuous methods in vertical, horizontal <strong>and</strong> inclined planeUNIT IVCorrosion <strong>and</strong> its prevention: Types of corrosion, causes of corrosion <strong>and</strong> methodfor combating corrosion.77

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