Note: Instruction for Examiner:The Semester examination in each theory subject shall be of 50 marks. The examiner will setnine questions. Student will attempt five questions. First question would be of short answertype question covering all four Units (2.5 Marks per Unit) & it would be compulsory. Twoquestions will be set from each unit & out of which c<strong>and</strong>idate will attempt one question. EachQuestion shall be of 10 marks.Suggested Readings (Latest Editions):1. I. L. Finar, “Organic Chemistry” (Vol. I <strong>and</strong> II), London: ELBS/ Longman.2. R. N. Acheson, “An Introduction to Chemistry of Heterocyclic Compounds”, NewDelhi: Interscience Publications.3. P. Sykes, “A Guide Book to Mechanism in Organic Chemistry”, New Delhi: OrientLongman.4. J. D. Roberts <strong>and</strong> M. C. Caserio, “Basic Principle of Organic Chemistry”, New York:W.A. Benjamin Inc.5. Jerry March, “Advanced Organic Chemistry: Reaction Mechanism <strong>and</strong> Structure NewChemistry”, U.S.A: Carrier publications.64
Paper Code: BPL-206Pharmaceutics-V (Pharmaceutical Microbiology)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives:Students are taught the principles of Microbiology with special reference to PharmaceuticalMicrobiology including environmental Microbiology <strong>and</strong> other relevant aspects. The modernconcepts of microbiological application are taught to students. The staining of slides <strong>and</strong>preparation of culture media, etc., including microbiological assays of pharmaceuticals is alsotaught. Sensitivity test <strong>and</strong> other necessary pharmaceutical tests are also included. Thestudents are trained about sterilization, disinfection <strong>and</strong> fermentation with reference to theiruse <strong>and</strong> application in the pharmaceutical industry. Knowledge of immune system is alsoimparted.UNIT IIntroduction to the science of microbiology: ancient theories concerning the originof life, contribution of great scientists to this science, with particular reference to thecontributions of the following scientists: A.V. Leeuwenhoek, Louis Pasteur, EdwardJenner, Robert Koch, Alex<strong>and</strong>er Fleming, Joseph Lister.Microscopy: Microscopes, their magnification, resolution, illumination <strong>and</strong> filters,working of different types of microscopes, micrometry.UNIT IIClassification of microbes <strong>and</strong> their taxonomy.Bacteria, fungi <strong>and</strong> viruses: Nutrition, cultivation, isolation <strong>and</strong> identification.Bacterial enzymes – classification, nomenclature, production by fermentation,extraction methods, immobilization techniques <strong>and</strong> applications of bacterial enzymesin general <strong>and</strong> detailed account of following bacterial enzymes: alpha amylase(diastase) <strong>and</strong> proteases.UNIT IIIDisinfection: factors affecting disinfection, dynamics of disinfection, disinfectants<strong>and</strong> antiseptics <strong>and</strong> their evaluation.Sterilization: Different methods, applications <strong>and</strong> evaluation of sterilization methods,aseptic technique.UNIT IVMicrobial st<strong>and</strong>ardization: Microbial st<strong>and</strong>ardization of antibiotics (ampicillin,streptomycin), Vitamins (Vitamin B-12, Niacin) <strong>and</strong> calcium pentothenate.Fermentation: Types of media used; factors affecting, control of various parametersduring fermentation. A detailed account of the industrial fermentation process formanufacture of penicillin, streptomycin, glutamic acid; Lysine, citric acid, Vit.B 12 .65
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BPS Mahila Vishwavidyalaya, Khanpur
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Types of closures used for the ster
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Suggested Readings (Latest Editions
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Suggested Readings (Latest Editions
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Paper Code: BPP-421Pharmacology-IV
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Paper Code: BPL-402Pharmaceutical C
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Paper Code: BPL-404Pharmaceutical C
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Paper Code: BPL-408Pharmacology-V (
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Paper Code: BPL-410Pharmacology-VI
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Paper Code: BPP-412Pharmaceutical C
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Paper Code: BPP-416Pharmaceutics -X