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Ordinance and Syllabus - Bhagat Phool Singh Mahila ...

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Paper Code: BPL-204Pharmaceutical Chemistry-VI (Organic Chemistry-II)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives: The area of application of Organic Chemistry is vast <strong>and</strong> includesPharmaceuticals. The objective of the paper is to review <strong>and</strong> study fundamentals of OrganicChemistry in identifying <strong>and</strong> synthesizing organic compounds essentially employed as drugs<strong>and</strong> pharmaceuticals. By studying this subject, the students usually underst<strong>and</strong> differentorganic reactions <strong>and</strong> their mechanisms. Knowledge about different organic molecules, theiruse in pharmacy <strong>and</strong> basic Terms <strong>and</strong> techniques in organic chemistry are highlighted.UNIT I: Heterocyclic compounds:UNIT IIStudy of fundamentals of heterocyclic compounds, nomenclature, method of synthesis<strong>and</strong> important chemical reactions of the following: Five membered Heterocycles:Furan, Thiophene, Pyrrole, Thiazole, oxazole, imidazole, Pyrazole. Six memberedHeterocycles: Pyridine, pyridazine, Pyrimidine, Pyrazine, Pyrones. Benz-fusedHeterocycles: Quinoline, Isoquinoline, Indole.Carbohydrates: An account of the chemistry of Arabonose, Ribose, mannose,Glucose, fructose, Sucrose, Lactose, Cellulose, starch, Glycogen <strong>and</strong> dextrans,Structure elucidation of glucose, sucrose, starch.Lipids: Study of chemistry of fixed oils, fats <strong>and</strong> waxes.UNIT IIIProteins <strong>and</strong> Amino Acids: Isolation <strong>and</strong> general methods of synthesis of aminoacids <strong>and</strong> physico-chemical properties. General classification of proteins <strong>and</strong> endgroup analysis.Structural features of DNA <strong>and</strong> RNA.UNIT IVα,β-Unsaturated carbonyl compounds.Electrocyclic, Cycloaddition <strong>and</strong>sigmatropic reactions.Neighbouring group effects.Catalysis by transition metal complexes.Stereoselective <strong>and</strong> stereospecific reactions.63

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