Ordinance and Syllabus - Bhagat Phool Singh Mahila ...

Paper Code: BPP-213 Pharmaceutical Chemistry-IV Practical (PharmaceuticalAnalysis-I)L -- T -- P Total Credits: 02-- -- 4 Total Marks: 100External Marks: 50Internal Marks: 50The students should be introduced to the main analytical tools through demonstrations. Theyshould have a clear understanding of a typical analytical balance, the requirements of a goodbalance, weights, care and use of balance, methods of weighing and errors in weighing. Thestudents should also be acquainted with the general apparatus required in various analyticalprocedures. Number of practicals based on theory portion should be conducted, some of themmay as follows:Standardization of analytical weights and calibration of volumetric apparatus.Acid Base Titrations : Preparation and standardization of acids and bases; someexercises related with determination of acids and bases separately or in mixture form,some official assay procedures e.g. boric acid should also be covered.Oxidation Reduction Tltrations: Preparation and standardization of some redoxtitrants e.g. potassium permanganate, potassium dichromate, iodine, sodiumthiosulphate, etc. Some exercises related to determination of oxidizing and reducingagents in the sample shall be covered. Exercises involving potassium iodate,potassium bromate, iodine solution, titanous chloride, and ceric ammonium sulphate.Precipitation titrations: Preparation and standardization of titrants like silver nitrateand, ammonium thiocyanate, Titrations according to Mohr's, Volhard's and Fajan'smethods.Gravimetric Analysis: Some exercises related to gravimetric analysis should becovered.Non aqueous Titrations: Preparation and standardization of perchloric acid andsodium/potassium/lithium methoxides solutions; Estimations of some pharmacopoeialproducts.Complexometric Titrations: Preparations and standardization of EDT A solution,some exercises related to pharmacopoeial assays by complexometric titrations.Suggested Readings (Latest Editions):1. A. I. Vogel, “Vogel’s Textbook of Quantitative Inorganic Analysis”, London: ELBS/Longman.2. I. M. Kolthoff and V. A. Stenger, “Volumetric Analysis, Vol. II Titration Methods”,New York: Interscience Publishers, Inc.3. Skoog, Hollar and Nieman, “Principles of Instrumental Analysis”, Philadelphia:Harcourt College Publishers.4. A. H. Beckett and J. B. Stenlake, “Practical Pharmaceutical Chemistry, Vol. I andII”, London: The Athlon Press of the University of London.5. L. G. Chatten, “Pharmaceutical Chemistry”, New York: Marcel Dekker.59