Paper Code: BPL-103 PHARMACEUTICAL CHEMISTRY-I (Inorganic Chemistry)L -- T -- P Total Credits: 044 -- -- Total Marks: 100External Marks: 50Internal Marks: 50Paper Objectives: Inorganic chemicals have been used in pharmacy <strong>and</strong> medicine for NewYork reasons ranging from therapeutic to nutritional supplements to pharmaceuticalnecessities. The paper is designed to study the principles of inorganic chemistry topharmaceuticals <strong>and</strong> to study those inorganic agents used as pharmaceutical aids <strong>and</strong>necessities or as therapeutics <strong>and</strong> diagnostic agents.UNIT IImpurities, Limit test for iron, lead, heavy metals, chloride & sulphate.An outline of the methods of preparation, uses, sources of impurities, tests for purity<strong>and</strong> identity <strong>and</strong> special tests if any, of the following classes of inorganicpharmaceuticals included in Indian Pharmacopoeia monograph details:• Gastrointestinal agents: Acidifying agents, antacids, protectives <strong>and</strong>adsorbents, cathartics;• Major extra <strong>and</strong> intra cellular electrolytes: Physiological anions,electrolytes used for replacement therapy, acid base balance <strong>and</strong> combinationtherapy.• Acids & Bases: Buffers, Water;UNIT IIEssential <strong>and</strong> trace elements: Transition elements <strong>and</strong> their compounds ofpharmaceutical importance: iron <strong>and</strong> haematinics, mineral supplements. Cationic <strong>and</strong>anionic compounds of inorganic drug useful for systemic effects.Topical agents: Protectives, astringents <strong>and</strong> anti-infectives.UNIT IIIGases <strong>and</strong> vapours: Oxygen, anesthetics <strong>and</strong> respiratory stimulants.8. Dentalproducts: dentifrices, anti-caries agent.Complexing <strong>and</strong> chelating agents used in therapy.Miscellaneous agents: Sclerosing agents, expectorants, emetics, poisons <strong>and</strong>antidotes, sedatives etc.UNIT IVPharmaceutical aids used in pharmaceutical industry: Antioxidants,preservatives,filter aids, adsorbents, diluents, excipients, suspending agents, colorants etc.Inorganic radiopharmaceuticals: Nuclear radiopharmaceuticals, reactions,nomenclature, methods of obtaining their st<strong>and</strong>ards <strong>and</strong> units of activity, measurementof activity, clinical applications <strong>and</strong> dosage, hazards <strong>and</strong> precautions.22
Note: Instruction for Examiner:The Semester examination in each theory subject shall be of 50 marks. The examiner will setnine questions. Student will attempt five questions. First question would be of short answertype question covering all four Units (2.5 Marks per Unit) & it would be compulsory. Twoquestions will be set from each unit & out of which c<strong>and</strong>idate will attempt one question. EachQuestion shall be of 10 marks.Suggested Readings (Latest Editions):1. A. I. Vogel, “Vogel’s Textbook of Quantitative Inorganic Analysis”, London: ELBS/Longman.2. J. H. Block, E. Roche, T. O. Soine <strong>and</strong> C. O. Wilson, “Inorganic Medicinal <strong>and</strong>Pharmaceutical Chemsitry”, Philadelphia PA: Lea <strong>and</strong> Febiger.3. “Pharmacopoeia of India”, Govt. of India, Ministry of Health.4. L.A. Diseher, “Modern Inorganic Pharmaceutical Chemistry”. New Delhi:Pharmacopoeia of India, Govt. of India, Ministry of Health, (All Edns.)23
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Paper Code: LAW- 001Legal LiteracyL
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Paper Code: BPP-313Pharmaceutics-VI
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Propanthaline bromide, Benzhexol, O
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Paper Code: BPP-314Pharmaceutics-VI
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Paper Code: BPP-318Pharmacology-III
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Nifedipine, Procainamide, Verapamil
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Packaging of Pharmaceutical Product
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Note: Instruction for Examiner:The
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UNIT IVAnti-epileptics drugs.Anti-P
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Types of closures used for the ster
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Paper Code: BPP-417Pharmaceutics -X
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Paper Code: BPP-421Pharmacology-IV
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Paper Code: BPL-402Pharmaceutical C
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Paper Code: BPL-410Pharmacology-VI
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