Clostridium Perfringens Type A, Toxoid Product Bulleting

PRODUCT BULLETINUALITY, The Mark Of ALicensed VaccineFor Veterinary Use OnlyCLOSTRIDIUM PERFRINGENSTYPE A, TOXOIDFor use as an aid in the control of necrotic enteritis caused by the alpha toxin ofClostridium perfringens in the progeny of pullets vaccinated prior to the onset of lay.For vaccination of healthy breeder replacement chickens at 10 to 15 weeks of agewith revaccination at 17 to 20 weeks of age. This product is conditionally licensedand efficacy studies are in progress.Advantages:■ Application of 2 doses toreplacement pullets prior to theonset of lay induces high titersthat are passed on to protectthe progeny■ Maternal antibodies againstalpha-toxin are known to reducemortality and to improve performancein affected broiler flocks■ Passive immunity against alphatoxinreduces lesions and protectsintestinal integrity in broilersClostridium perfringens Type A toxoid for subcutaneousor intramuscular injection of breederreplacement pullets as an aid in the control ofnecrotic enteritis in their broiler progeny.Supplied in 1000 dose bottles.■ Cost-effective: one 500 mL bottlewill vaccinate 1000 pullets andprotect sixty-five thousandbroilers or more** Based on 130 chicks per hen

CLOSTRIDIUM PERFRINGENSTYPE A, TOXOIDFor Veterinary Use OnlyWhen to VaccinateVaccinate breeder replacement pullets via subcutaneousor intramuscular injection initially at 10 to 15weeks of age with revaccination at 17 to 20 weeksof age.Your Vaccination ProgramThe development of a durable, strong antibodyresponse to this toxoid vaccine depends upon the useof an effective vaccination program as well as manycircumstances such as administration techniques,environment and flock health at the time of vaccination.Also, the immune response to one vaccinationunder field conditions is seldom complete for all animalswithin a given flock. Even when vaccination issuccessful, the protection stimulated in individual animalsagainst different diseases may not be life long.Therefore, a program of revaccination may benecessary.Dosage and AdministrationAllow the vaccine to reach ambient temperature,16-27 o C (60-80 o F), before use and shake vigorouslybefore and periodically during use. Inject 0.5 mL intramuscularlyor subcutaneously in chickens using an 18gauge x 1 ⁄2” or 1 ⁄4” needle.Precautions1. For veterinary use only.2. Vaccine should be stored at 2-7 o C (35-45 o F).DO NOT FREEZE.3. Do not vaccinate within 60 days of slaughter.4. Vaccinate only healthy birds.5. Do not mix this vaccine with any other substances.6. Vaccination equipment must be cleaned andsterilized before use. Do not use vaccinationequipment with rubber parts, as the oil emulsionmay degrade certain types of rubber.7. Use entire contents of vial when first opened.8. Wash hands thoroughly after using the vaccine.9. Do not dilute the vaccine or otherwise stretchthe dosage.10. Transient local reaction may occur at theinjection site.Contains Gentamicin and thimerosal as preservatives.WarningExtreme caution should be used when injectingoil emulsion vaccines to avoid injecting your ownfinger or hand. Accidental injection can causeserious local reaction. Contact a physician immediatelyif accidental injection occurs.Ask your Schering-Plough Animal Health salesor technical services representative to design a customvaccination control program to meet your needs.Summit, NJ 07901Copyright © 2006, Schering-Plough Animal Health Corporation. All rights reserved.SPAH-PBU-423