Patterned and switchable surfaces for biomaterial applications

Andrew Hook – Patterned and switchable surfaces for biomaterial applicationsFigure 1.2. SEM images of OCT-1 osteoblasts on different pits-patterned PS surface.(A) on micro-scale (2.2 m) pits PS (8000x mag.) cells were observed to beable to stride over pits; (B) on micro-scale (2.2 m) pits PS (15000x mag.)pseudopods of the cells were observed to enter into the pits and grow alongthe ridge at the wall of the pits instigating contact guidance of the attachedcell; (C) on micro-scale (2.2 m) pits PS (5000x mag.) filopodia of attachedcells grew along the ridge at the wall of the pits instigating contact guidanceof the attached cell and altering cell morphology; (D) on nano-scale pits(0.45 m) PS (80000x mag.) cells tended to stride over these smallerfeatures. From [63].1-15