Patterned and switchable surfaces for biomaterial applications

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Chapter 6 – Overall conclusionsnew materials for specific biomedical applications, particularly since biomolecularand cellular interactions with material surfaces are complex and difficult to predict apriori.In summary, a number of biodevice applications will benefit from the furtherdevelopment of biomolecular manipulation and an advanced understanding of theinterface behaviour of biomolecules and cells. Here, it has been demonstrated thatthis can be achieved by introducing both patterned and switchable elements in orderto both spatially and temporally control the complex biological systems thatbiodevices interact with, coupled with the development of tools to analyse in depththe surface behaviour of biomolecules and living cells.6-212
Andrew Hook – Patterned and switchable surfaces for biomaterial applicationsAPPENDIX 1.LIST OF ABBREVIATIONS2D3D DNA proteinCPAAmACPAAFMALAPPAOLGAPTMSBAEcBCEpBSACCDcDNACHO-K1CNCOSDCDMEMDMSDMSODNADPNdsDNAEC bufferECME-coliEDCEDSEDTAFAMFDAFITCFNFT-IRGFPGPCRsHDIHeLaHEKIgGLCST7.8.Two dimensionalThree dimensionalSurface coverage of DNASurface coverage of proteinMicrocontact printingAcrylamide4,4'-azobis(4-cyanopentanoic acid)Atomic force microscopyAllylamine plasma polymerAmino-oligonucleotide3-aminopropyltrimethoxysilaneBovine aortic endothelial cellsBovine corneal epithelial cellsBovine serum albuminCharge coupled detectorComplementary DNAChinese hamster ovary cell lineCollagenMonkey kidney fibroblastsDirect currentDulbecco’s modified eagle mediaDimethyldichlorosilaneDimethylsufoxideDeoxyribonucleic acidDip-pen nanolithographyDouble stranded DNACondensation bufferExtra cellular matrixEscherichia coli1-ethyl-3-(diethylamino)propyl carbodiimideN-(2-aminoethyl)-3-aminopropyltrimethoxysilaneEthylenediaminetetraacetic acidCarboxyfluoresceinFluorescein diacetateFluorescein isothiocyanateFibronectinFourier transform – infraredGreen fluorescing proteinG-protein coupled receptorsHexamethylene diisocyanateHenrietta LackHuman embryonic kidney cellImmunoglobulinLower critical solution temperatureA
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Patterned andswitchable surfacesfor
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TABLE OF CONTENTSTABLE OF CONTENTS
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CHAPTER 1.INTRODUCTION1The content
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Chapter 1 - Introductionconsiderabl
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Chapter 1 - Introductioninteraction
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Chapter 1 - IntroductionIn general,
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Chapter 1 - IntroductionFor some ap
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Chapter 1 - Introductionangles rang
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Chapter 1 - Introductionof understa
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Chapter 1 - IntroductionSeveral str
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Chapter 1 - Introductioncues to con
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Chapter 1 - Introductionby controll
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Chapter 1 - Introduction1.2.2. Soft
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Chapter 1 - Introductionsubstrate.
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Chapter 1 - Introduction(A)(B)Figur
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Chapter 1 - Introduction(A)(B)(C)(C
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Chapter 1 - Introductioncomplex gen
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Chapter 1 - Introductionmorphology
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Chapter 1 - Introduction(A)(B)(C)(D
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Chapter 1 - Introductionthe LCST, a
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Chapter 1 - IntroductionHyun et al.
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Chapter 1 - Introductionmicelles. T
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Chapter 1 - Introduction1.4.1. DNA
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Chapter 1 - IntroductionA major pro
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Chapter 1 - Introductionattached to
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Chapter 1 - IntroductionTable 1.1.
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Chapter 1 - Introductionefficiencie
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Chapter 1 - Introductionachieved by
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Chapter 1 - IntroductionTable 1.2.
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Chapter 1 - IntroductionOnce releas
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Chapter 1 - Introductionimaging not
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Chapter 1 - IntroductionA number of
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CHAPTER 2.SPATIALLY CONTROLLED ELEC
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CHAPTER 3.COMPARISON OF THE BINDING
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DNA (mg/m 2 ) DNA (mg/m 2 )Andrew H
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DNA (mg/m 2 )Andrew Hook - Patterne
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Chapter 4 - Formation of a chemical
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CHAPTER 5.SURFACE PLASMON RESONANCE
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Patterned and switchable surfaces for biomaterial applications

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