13.07.2015 Views

Patterned and switchable surfaces for biomaterial applications

Patterned and switchable surfaces for biomaterial applications

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Chapter 5 – Surface plasmon resonance imaging of polymer microarraysThe results demonstrate the ability of the label-free technique SPRi to achieveuseful kinetic <strong>and</strong> thermodynamic insights into the biomolecular behaviour within apolymer microarray <strong>for</strong>mat without the need <strong>for</strong> advanced fabrication approaches toensure a homogeneous surface. Use of a larger polymer library would allow <strong>for</strong> thehigh-throughput determination of the suitability of particular materials <strong>for</strong> specificbiomedical <strong>applications</strong>, including tissue engineering, drug delivery <strong>and</strong> implantdevelopment, <strong>and</strong> would engender insights into the underlying mechanisms ofbiomolecular adsorption <strong>and</strong> cell attachment.5-206

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