Biofeedback and other Therapies for the Treatment of Urinary ...

Biofeedback and other Therapies for the Treatment of Urinary ... Biofeedback and other Therapies for the Treatment of Urinary ...

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ReviewUrinary IncontinenceStress IncontinenceConventional Treatments for StressSI is the second-most frequent form of incontinencein women. 1 SI results when laxity in theConventional treatments for SI include pel-Incontinencemuscles of the pelvic floor, loss of urinary sphincterfunction, or urethral closure fails to prevent urine two studies, the combination of exercise and educavicfloor muscle exercises and reparative surgery. Infrom leaking from the bladder. 1 Childbirth-related tion about the function and anatomy of the urinarytrauma is a common cause of pelvic muscle injury tract decreased incontinence by 88 6 and 94 7 percent,that ultimately predisposes to SI. 2 SI can also occur respectively. However, two other studies found no additionalbenefit from the combination after surgery. 8,9in men who have had prostate surgery. 4 The incidenceof SI following prostate surgery varies widely fromSuccess rates of surgical treatments for incontinencefollowing prostatectomy vary widely. In0.3-65.6 percent, possibly due to differences in surgicaltechnique. 5a series of small studies – less than 50 patients perstudy – continence was restored in 36-95 percent ofOverflow Incontinencesubjects. 10-15OI is the second-most common form of incontinencein men. 1 It usually results when the outflowfrom the bladder is blocked by structures distalConventional Treatments for OverflowIncontinenceto the bladder (in men usually an enlarged prostate). 1OI is typically treated with medication or surgery.Urinary pressure builds in the bladder until it exceedsthe ability of the musculature surrounding the bladder1 In published trials of the treatments for symptomaticrelief of benign prostatic hypertrophy, theto maintain continence, causing leakage. 1incidence of OI has been rather low – less than oneevent per patient per year – making evaluation of suchConventional Treatmenttreatments difficult. In these trials, neither surgery norConventional treatments consist of behavioraltherapy, exercises to strengthen the pelvic floormedication decreased the incidence of OI. 16,17muscles, medications, or surgery. 1Alternative TreatmentsSince no conventional therapy is completelyConventional Treatments for Urgeefficacious and older individuals may be unwillingIncontinenceor unable to undergo surgical treatment, alternativeUR is treated either by behavioral therapy treatments may potentially be used as primary or adjunctivetherapy to reduce the number of episodes ofor medication. Behavioral therapies, although nota cure, can decrease the incidence of incontinence. UI. While conventional non-surgical treatments canTherapies may include habit training consisting of eitherscheduled voiding based on a person’s usual toi-Assessment and comparison of the efficaciesbe efficacious, the cure rate is less than 50 percent. 18leting schedule (which can result in at least a 25-percentdecrease in episodes of incontinence) or specific hindered by lack of a standardized definition of UIof alternative therapies in different studies have beeninterval toileting schedules every 2-3 hours (which in the subject populations, lack of standardization ofcan reduce episodes by as much as 80 percent). 1treatments and treatment protocols, inadequate samplesizes, and lack of blinding and appropriate con-The most effective medications, includingoxybutinin and tolterodine, inhibit bladder muscle trols.contractions, reduce episodes of incontinence by approximately70 percent, and have a cure rate of about20 percent. 1Alternative Medicine Review u Volume 11, Number 3 u 2006 Page 225Copyright © 2005 Thorne Research, Inc. All Rights Reserved. No Reprint Without Written Permission. Alternative Medicine Review Volume 10, Number 4 December 2005

Urinary IncontinenceReviewBiofeedback and Pelvic Exercise forUrinary IncontinenceBiofeedback is the most extensively studiedunconventional therapy for UI. In the application ofbiofeedback to treat UI, surface or internal electrodescreate visual or auditory signals when pelvic musclesare contracted. Using these signals, subjects can learnto augment or reduce muscle contractions voluntarilythrough muscle exercises to maintain continence. Thetechniques used in the various studies differ in regardto location of the electrodes (intravesicular, anal, orurethral sphincter), type of signal, (auditory or visual),and duration of training. 19Biofeedback/Pelvic Floor Exercises for UrgeIncontinenceBoth controlled and uncontrolled trials havecompared pelvic exercises with and without biofeedbackin limited numbers of subjects with UR; noresults of placebo-controlled trials have been published.In a small study, biofeedback reduced urinaryincontinence symptom scores and improved bladdermuscle pressure in 10 subjects, ages 24-53. 20 In a secondstudy, women (ages 16-65 years; mean age 41)were administered biofeedback for an average of fivesessions with an 87-percent cure rate. 21,22Wang et al compared biofeedback-assistedpelvic floor muscle exercises to either pelvic floormuscle exercise alone or exercise aided by electricalstimulation of the pelvic floor musculature via an intravaginalelectrode in 103 women (ages 15-71 years)for 12 weeks. 23 There was a significant improvementin symptom score in biofeedback-assisted pelvic floorexercises above that achieved by pelvic floor muscleexercises alone; however, the cure rate was not significantlydifferent among the three groups. Althoughindividuals in the electrical-stimulation group experiencedthe most improvement, the subjects in thisgroup were significantly younger than women in theother two groups.In a second study, 30 of 70 women who failedmedication as therapy for UR were offered either biofeedbackor pelvic floor muscle exercises. 24 Biofeedbackrecipients exhibited greater bladder detrusormuscle pressures, although there was no differencein cure rate.Biofeedback for Stress IncontinenceBiofeedback has also been used alone or incombination with conventional therapy to treat stressincontinence. Although the pelvic muscle exercisesthat are the mainstay of conventional therapy for SIbear the name of Dr. Arnold Kegel (Kegel exercises), 19Kegel did not develop these exercises, but invented abiofeedback device to use with the exercises. 19 Usinghis device, he reported to have eradicated symptomsin 93 percent of incontinent individuals. 19Pages et al performed a randomized, controlled,four-week trial on 40 women (ages not reported)with SI. They compared biofeedback andphysical therapy followed by two weeks of home exercises.The physical therapy group received 20 onehoursessions of practice in pelvic muscle exerciseswith education on the anatomy and function of thebladder. Subjects who received biofeedback experienceddecreased urinary frequency and subjectiveimprovement on symptom scores. 25In a controlled investigation, 130 women(mean age 60) were randomized to receive biofeedback,pelvic floor muscle exercises, or no treatmentfor six months. Compared to the control group, bothinterventional arms experienced equal statisticallysignificant reductions in episodes of incontinence. 26Thirty-five women (ages 31-69 years; meanage 50) were randomized to utilize pelvic floor muscleexercises with or without home biofeedback. After12 weeks, the biofeedback group obtained significantimprovement on a self-reported questionnaire scaleof urinary leakage. 27In several small, uncontrolled studies involving28-60 women, subjects observed both symptomreduction and improved contractility of pelvic floormusculature. 28-30Not all studies have noted positive results. Ina randomized study, 103 women (ages 30-70; meanage 46.6) received pelvic floor muscle training withor without biofeedback. 31 No differences were notedbetween groups in any of the measures studied.In another study, 44 subjects were randomizedto receive six treatments of pelvic floor exerciseswith or without biofeedback. Both groups improved,but no statistically significant differences were notedbetween the groups at the end of the trial. 32Page 226 Alternative Medicine Review u Volume 11, Number 3 u 2006Copyright © 2005 Thorne Research, Inc. All Rights Reserved. No Reprint Without Written Permission. Alternative Medicine Review Volume 10, Number 4 December 2005

Review<strong>Urinary</strong> IncontinenceStress IncontinenceConventional <strong>Treatment</strong>s <strong>for</strong> StressSI is <strong>the</strong> second-most frequent <strong>for</strong>m <strong>of</strong> incontinencein women. 1 SI results when laxity in <strong>the</strong>Conventional treatments <strong>for</strong> SI include pel-Incontinencemuscles <strong>of</strong> <strong>the</strong> pelvic floor, loss <strong>of</strong> urinary sphincterfunction, or urethral closure fails to prevent urine two studies, <strong>the</strong> combination <strong>of</strong> exercise <strong>and</strong> educavicfloor muscle exercises <strong>and</strong> reparative surgery. Infrom leaking from <strong>the</strong> bladder. 1 Childbirth-related tion about <strong>the</strong> function <strong>and</strong> anatomy <strong>of</strong> <strong>the</strong> urinarytrauma is a common cause <strong>of</strong> pelvic muscle injury tract decreased incontinence by 88 6 <strong>and</strong> 94 7 percent,that ultimately predisposes to SI. 2 SI can also occur respectively. However, two <strong>o<strong>the</strong>r</strong> studies found no additionalbenefit from <strong>the</strong> combination after surgery. 8,9in men who have had prostate surgery. 4 The incidence<strong>of</strong> SI following prostate surgery varies widely fromSuccess rates <strong>of</strong> surgical treatments <strong>for</strong> incontinencefollowing prostatectomy vary widely. In0.3-65.6 percent, possibly due to differences in surgicaltechnique. 5a series <strong>of</strong> small studies – less than 50 patients perstudy – continence was restored in 36-95 percent <strong>of</strong>Overflow Incontinencesubjects. 10-15OI is <strong>the</strong> second-most common <strong>for</strong>m <strong>of</strong> incontinencein men. 1 It usually results when <strong>the</strong> outflowfrom <strong>the</strong> bladder is blocked by structures distalConventional <strong>Treatment</strong>s <strong>for</strong> OverflowIncontinenceto <strong>the</strong> bladder (in men usually an enlarged prostate). 1OI is typically treated with medication or surgery.<strong>Urinary</strong> pressure builds in <strong>the</strong> bladder until it exceeds<strong>the</strong> ability <strong>of</strong> <strong>the</strong> musculature surrounding <strong>the</strong> bladder1 In published trials <strong>of</strong> <strong>the</strong> treatments <strong>for</strong> symptomaticrelief <strong>of</strong> benign prostatic hypertrophy, <strong>the</strong>to maintain continence, causing leakage. 1incidence <strong>of</strong> OI has been ra<strong>the</strong>r low – less than oneevent per patient per year – making evaluation <strong>of</strong> suchConventional <strong>Treatment</strong>treatments difficult. In <strong>the</strong>se trials, nei<strong>the</strong>r surgery norConventional treatments consist <strong>of</strong> behavioral<strong>the</strong>rapy, exercises to streng<strong>the</strong>n <strong>the</strong> pelvic floormedication decreased <strong>the</strong> incidence <strong>of</strong> OI. 16,17muscles, medications, or surgery. 1Alternative <strong>Treatment</strong>sSince no conventional <strong>the</strong>rapy is completelyConventional <strong>Treatment</strong>s <strong>for</strong> Urgeefficacious <strong>and</strong> older individuals may be unwillingIncontinenceor unable to undergo surgical treatment, alternativeUR is treated ei<strong>the</strong>r by behavioral <strong>the</strong>rapy treatments may potentially be used as primary or adjunctive<strong>the</strong>rapy to reduce <strong>the</strong> number <strong>of</strong> episodes o<strong>for</strong> medication. Behavioral <strong>the</strong>rapies, although nota cure, can decrease <strong>the</strong> incidence <strong>of</strong> incontinence. UI. While conventional non-surgical treatments can<strong>Therapies</strong> may include habit training consisting <strong>of</strong> ei<strong>the</strong>rscheduled voiding based on a person’s usual toi-Assessment <strong>and</strong> comparison <strong>of</strong> <strong>the</strong> efficaciesbe efficacious, <strong>the</strong> cure rate is less than 50 percent. 18leting schedule (which can result in at least a 25-percentdecrease in episodes <strong>of</strong> incontinence) or specific hindered by lack <strong>of</strong> a st<strong>and</strong>ardized definition <strong>of</strong> UI<strong>of</strong> alternative <strong>the</strong>rapies in different studies have beeninterval toileting schedules every 2-3 hours (which in <strong>the</strong> subject populations, lack <strong>of</strong> st<strong>and</strong>ardization <strong>of</strong>can reduce episodes by as much as 80 percent). 1treatments <strong>and</strong> treatment protocols, inadequate samplesizes, <strong>and</strong> lack <strong>of</strong> blinding <strong>and</strong> appropriate con-The most effective medications, includingoxybutinin <strong>and</strong> tolterodine, inhibit bladder muscle trols.contractions, reduce episodes <strong>of</strong> incontinence by approximately70 percent, <strong>and</strong> have a cure rate <strong>of</strong> about20 percent. 1Alternative Medicine Review u Volume 11, Number 3 u 2006 Page 225Copyright © 2005 Thorne Research, Inc. All Rights Reserved. No Reprint Without Written Permission. Alternative Medicine Review Volume 10, Number 4 December 2005

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