Paediatric cardiology clinical profile - University Hospital ...

DIGOXINUses :Dose :Side-effects :Interactions :Notes :Management of Atrial Flutter and SVTTreatment of CCFSlows and steadies the heart rate, allowing greater filling time, stronger contractionsand improved cardiac outputInitial loading dose (not IV)Maintenance 5mcg/kg BD, orallyToxicity leading to lethal arrhythmiasLevels may increase if used along-side Amiodarone, Flecainide and SpironolactoneRisk of toxicity is increased if used along-side diureticsContra-indicated in patients with heart block and Wolff-Parkinson-WhitesyndromeBlood level needs to be monitored to prevent toxicityFLECAINIDEUses :Dose :Interactions :Notes :Treatment and management of SVT, VT and ventricular ectopics2mg/kg TDS IV bolus or oral100-250mcg/kg/hr IV infusionIncreases Digoxin levelReduces effect of Beta BlockersDoubles effect of AmiodaroneCo-enhances effect if given with PropranololContra-indicated in patients with AF, SA Node Dysfunction, Heart Block, or BundleBranch Block