Paediatric cardiology clinical profile - University Hospital ...

WARFARINUses :Dose :Anticoagulant1)Used in management of Prosthetic valves2)Used in management of Fontana circulation3)Used in management of cardiomyopathy and in some conditions where risk ofpooling and turbulent flowUsually 100-200mcg/kg daily, orallyDose varied according to INRTarget INR Values :1) 3 – 42) 2 – 33) 2 – 3NB. Normal INR 0.8 – 1.2Side-effects :Risk of excessive bleeding and bruisingRisk of haemoptysisRashHair lossInteractions :Notes :Aspirin, NSAID’s, and Amiodarone and antibiotics can all affect INR and worsensymptomsMonitored on venous blood sample in hospital, dose adjusted accordingly. Usuallytested weeklyPatient may have home Coaguchek machine which tests on capillary blood sample