Volume of Distribution Prediction: Physiologically Based ...
Volume of Distribution Prediction: Physiologically Based ...
Volume of Distribution Prediction: Physiologically Based ...
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patrick-poulin@videotron.ca P. Poulin. April, 2007.<strong>Distribution</strong> <strong>Prediction</strong> AAPS – November 11, 2009First Mechanistic/Physiological<strong>Prediction</strong> method <strong>of</strong> <strong>Distribution</strong>Volatile Organic Chemicals (VOCs) in the EnvironmentMETHOD YNeutral VOCsLipophilicityNeutral lipidsKp(tissue:air PC)