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marker-assisted selection in wheat

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Chapter 18 – Marker-<strong>assisted</strong> <strong>selection</strong> <strong>in</strong> crop and livestock improvement 377planned outputs will eventually lead tothe creation of many new products andprocesses of commercial value. Thus, theactivities dur<strong>in</strong>g its first phase are designedto resolve basic, common technologicalproblems – a sufficient reason to mobilizeseveral private companies (that arecompetitors <strong>in</strong> the market) and publicorganizations. After the first phase of sixyears, the network will have generated aconsolidated base of knowledge and toolsthat will promote the development of specific<strong>in</strong>terest projects, either <strong>in</strong> partnershipor <strong>in</strong>dividually, accord<strong>in</strong>g to specific bus<strong>in</strong>essstrategies and market targets.Also, team organization and managementare based on modern tools andconcepts, <strong>in</strong>volv<strong>in</strong>g a competent, highlyrespected scientist with talent to lead networkoperations, a steer<strong>in</strong>g committee anda technical committee for adequate plann<strong>in</strong>g,decision-mak<strong>in</strong>g and follow-up, aswell as contract models and negotiationstrategies appropriate to the complexity ofthe network. Intellectual property rightsprovisions are based on access limited toparticipants, with all genetic materials andpatents produced be<strong>in</strong>g co-owned by the20 participat<strong>in</strong>g <strong>in</strong>stitutions. Scientific publicationsare highly encouraged.As <strong>in</strong> the Generation ChallengeProgramme, the Genolyptus network is anorig<strong>in</strong>al <strong>in</strong>itiative to <strong>in</strong>tegrate and align acomplex mix of tools, capacities, conceptsand strategies. The ability to mobilize sucha wide range of organizations, <strong>in</strong>clud<strong>in</strong>g12 private companies operat<strong>in</strong>g <strong>in</strong> a highlycompetitive market space, <strong>in</strong>dicates that thenetwork design was successful, while itspre-competitive nature, organization andmanagement strategy allowed the def<strong>in</strong>itionof a “zone of mutual benefits” (Figure 3),facilitat<strong>in</strong>g the pursuit of goals that are notatta<strong>in</strong>able through isolated research. TheGenolyptus network is therefore an excellentexample of the feasibility of develop<strong>in</strong>ga structured public/private effort for <strong>in</strong>tegratedand effective use of advanced toolssuch as MAS.Conclusions• Although advances <strong>in</strong> molecular <strong>marker</strong>technology have uncovered many possibilitiesfor eas<strong>in</strong>g the transfer of genes<strong>in</strong>to desired crops and livestock throughMAS, there is still limited recordedimpact of these technologies <strong>in</strong> breed<strong>in</strong>gprogrammes.• It is generally recognized that geneticimprovement of complex traits us<strong>in</strong>gMAS is more difficult than previouslyconsidered. Therefore, more methodologydevelopment, better plann<strong>in</strong>g andimplementation strategies will be neededfor its successful and rapid application tobreed<strong>in</strong>g programmes.• The future configuration of breed<strong>in</strong>gprogrammes is dependent on knowledgeto guide strategic decisions aboutstructures, methods and capacities thattake advantage of new opportunitiesand technological niches. Unfortunately,there are very few efforts directed atth<strong>in</strong>k<strong>in</strong>g about the future of breed<strong>in</strong>gprogrammes, especially <strong>in</strong> less developedcountries. Research organizations need<strong>in</strong>formation, which is not currently available,about changes and <strong>in</strong>fluences andtheir impact <strong>in</strong> the future on key activitiessuch as crop and livestock breed<strong>in</strong>g.To acquire and organize this <strong>in</strong>formation,prospective studies on the presentand future performance of breed<strong>in</strong>g programmesand their related activities willhave to be developed.• Priority-sett<strong>in</strong>g strategies, together withcost–benefit analysis are necessary toguide <strong>in</strong>formed decisions on how best

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