THE FLAVOR AND EXTRACT MANUFACTURERS ASSOCIATIONATTENTION - Safe flavors can beused in an unsafe manner. Pleasecontact your workplace safety officerbefore opening and handling thisflavor, and read the MSDS.Flavor manufacturers and suppliers cannotin all instances know how their customer willuse a flavoring material. In many instances, thecustomer chooses to keep information related tohow they will use a flavoring material confidentialto protect valuable trade secret informationrelated to their products. In other instances, customersmay communicate to a supplier how theyplan to use a flavor but then modify their plans.The warning statements suggested in this sectionprovide a means for flavor manufacturersto assure their customers receive helpful informationrelated to the safe handling and use offlavors.Important resources on the subject ofmanagement and employee awareness include:■■ The OSHA Hazard Communications Standard.■ ■ OSHA GHS Implementation Program.■■ Hazard Communication Guidance for Diacetyland Food Flavorings Containing Diacetyl(OSHA, 2007).■■ Occupational Exposure to Flavoring Substances:Health Effects and Hazard Control(OSHA, 2010).■■ OSHA National Emphasis Program forFacilities that Manufacture Food FlavoringsContaining Diacetyl (OSHA, 2011).Exposure Assessmentand ControlAssessment of potential exposuresEnvironmental monitoring is a necessarycomponent of a sound respiratory healthand safety program. Monitoring at regular intervalscan provide valuable information on potentialexposures. In addition to monitoring forthe presence of certain vapors in air, monitoringof particulates, when appropriate, should also beconducted if reliable methods are available. Acritical issue in any monitoring program is identifyingthe appropriate substances to monitor.NIOSH has focused on diacetyl and 2,3-pentanedioneand provides a thorough discussionof analytical methods and sampling in the draftreport Occupational Exposure to Diacetyl and2,3-Pentanedione (NIOSH, 2011). Also relevantare reports by Cox-Gansler et al. (2011)and Day et al. (2011).Exposure controlFlavor manufacturing facilities varygreatly in size, structure, age, manufacturingtechnologies employed, flavoring substancesstocked and handled, types of flavors manufactured,and many other characteristics. Manufacturingprocesses may range from simpleblending and packaging to more complicatedprocesses that include repeated heating of flavoringsubstances that are mixed and heatedagain, extraction at room temperature and withheat, and other processes that may result in significantopportunities for exposure.Some facilities have extensive automatedprocesses that minimize opportunities for exposurewhile others have little automation and7
RESPIRATORY HEALTH AND SAFETY IN THE FLAVOR MANUFACTURING WORKPLACErely on workers manipulating large quantities offlavors and other materials by hand during theformulation and packing processes. Because ofthis great variability, “one size fits all” solutionsto material handling strategies and engineeringcontrols is inappropriate. However, a number ofbasic principles can greatly reduce opportunitiesfor hazardous exposures.Product substitutionAwareness that specific substances arehazardous often results in the application of asimple industrial hygiene strategy – productsubstitution. Product substitution may be employedwhen it is known that a substance is hazardousand can be replaced with one that isn’t.The unique nature of the flavor imparted by certainsubstances, many of which are naturally occurringconstituents of food, makes it difficult toidentify substitutes that are effective.In 2010 OSHA published a “WorkerAlert” on diacetyl and substitutes noting that“some diacetyl substitutes may also cause harm.”The Alert stated, “Diacetyl substitutes that havenot been proven to be safe include diacetyltrimer, 2,3-hexanedione, 2,3-heptanedione, and2,3-pentanedione.” In January, 2011, NIOSHrequested information on flavoring substancesthat may be used as substitutes for diacetyl (76Fed. Reg. 1434. 10 January 2011). FEMA providedinformation to NIOSH on six flavoringsubstances that it was aware of that may serveas substitutes for diacetyl:■■ Four alpha-diketone substances: 2,3-pentanedione,2,3-hexanedione, 3,4-hexanedione,and 2,3-heptanedione.■■ Two other related substances: acetoin anddiacetyl trimer.NIOSH published results from environmentalmonitoring at a microwave popcorn productionplant focusing on the possible presenceof “diacetyl substitutes” (Boylstein, <strong>2012</strong>).Heating of flavorsHeating of flavors is of particular concernwith regard to potential hazardous exposures.Heating will increase volatility andgreatly increase air concentrations of flavoringsubstances. Mixing of heated flavors should beconducted in closed vessels with local ventilation.Workers should not open heated vessels toconduct visual inspections in such a way as tocreate an opportunity for exposure. In instanceswhen workers must work near open vesselsthat are heated and cannot be closed or do nothave local ventilation, their exposures should bepromptly evaluated by environmental sampling.If exposures are elevated then the proper personalprotective equipment should be employed.Facility structure and organizationOpportunities for exposure can be greatlydecreased by segregating functions that involvethe handling of flavors from functions that donot. For example, a flavor compounding, packing,or shipping area should not share space witha sales office. Flavor production areas shouldbe separate from non-production areas and theyshould not share the same air handler.VentilationFlavoring substances and mixtures,whether liquid or dry, must be handled in sucha way as to minimize the creation of airborneaerosols or particulate matter. This means thatmixing, blending, and other physical manipulationactivities should be performed in closed8