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Alain Stricker-Krongrad, PhD

Alain Stricker-Krongrad, PhD

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5/14Ciba-Geigy, Basel, Switzerland1995-1996 Research Fellow, Metabolic and Cardiovascular Diseases• Designed and performed pilot studies of compounds on CV, CNS and neurocrine axis ex vitro andin animal models• Developed and validated immunoassays for measuring circulating hormones• Set up studies to examine the interactions of compounds with reproductive axis in rodents• Initially supervised one laboratory assistant and a <strong>PhD</strong> studentBoots Pharmaceuticals, Courbevoie, FranceINSERM U308, Nancy, France1993 - 1995 Postdoctoral Fellow• Designed and performed preclinical animal studies demonstrating the new therapeutic utility ofBTS 54524 (sibutramine, now marketed as Meridia, US and Reductil, Europe)• Designed and performed efficacy animal studies demonstrating the CNS profile of peptidicneuropeptide antagonists and agonist• Performed the statistical validation of the Dutch Eating Behavior Questionnaire in a Frenchpopulation (clinical assessment of eating disorders)• Supervised undergraduate students and one laboratory assistantACADAMIC DISTINCTIONS:Society for the Study of Ingestive Behavior’sYoung Investigator AwardPrinceton University 1992Society for the Study of Ingestive BehaviorInternational Association for the Study of Obesity’sInternational Young Investigator Competition AwardToronto 1994International Association for the Study of ObesityPATENTS:<strong>Stricker</strong>-<strong>Krongrad</strong> A and Wei G.USP 6,197,530 GPR10 as a target for identifying weight modulating compounds.Acton S, et al. and <strong>Stricker</strong>-<strong>Krongrad</strong> A.WO 02/39997 ACE-2 modulating compounds and methods of use thereofWhite DW, et al. and <strong>Stricker</strong>-<strong>Krongrad</strong> A.WO 02/074905 Leptin induced genesTartaglia LA and <strong>Stricker</strong>-<strong>Krongrad</strong> A.USPA 20030053951 Use of non-invasive imaging technologies to monitor in vivo geneexpression<strong>Stricker</strong>-<strong>Krongrad</strong> A and Wei G.

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