Nepal Elephant TB Control and Mgt Action Plan.pdf - Elephant Care ...

Nepal Elephant Tuberculosis Control andManagement Action Plan (2011-2015)B. Full Treatment for Group 3 Elephants: three drugs for two months followed by two drugs for 10months1. Oral protocolINH-RIF:Dose /day: 5mg/kg/day x 3000 kg = 15,000 mgTablets/day: 15,000 mg / 300 mg / tablet = 50 tabletsTotal # of tablets: 50 tablets / day X 360 days = 18,000 tabletsTotal cost: 18,000 tablets @ Rs 8.6 /tablet = Rs 154,800 (plus replacements for wasted drugs).EMB:Dose /day: 30mg/kg/day x 3000 kg = 90,000 mgTablets/day: 90,000 mg / 800 mg / tablet = 112 tabletsTotal # of tablets: 112 tablets / day X 60 days = 6720 tabletsTotal cost: 6720 tablets @ Rs 6.1 /tablet = Rs 40,992 (plus replacements for wasted drugs).Total cost: Rs 195,7922. Rectal protocol (more expensive; use only if oral therapy cannot be managed)INH:Dose /day: 5mg/kg/day x 3000 kg = 15,000 mgTablets/day: 15,000 mg / 300 mg / tablet = 50 tabletsTotal # of tablets: 50 tablets / day X 360 days = 18,000 tabletsTotal cost: 18,000 tablets @ Rs 2 /tablet = Rs 36,000 (plus replacements for wasted drugs).EMB:Dose /day: 30mg/kg/day x 3000 kg = 90,000 mgTablets/day: 90,000 mg / 800 mg / tablet = 112 tabletsTotal # of tablets: 112 tablets / day X 360 days 40,320 tabletsTotal cost: 40,320 tablets @ Rs 6.1 /tablet = Rs 245,952 (plus replacements for wasted drugs).Ciprofloxacin: 5-10mg/kg (empirical dose) or Amikacin (injectable): to be discussed with TB PlanVeterinary Officer on a case-by-case basis.33