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Nepal Elephant TB Control and Mgt Action Plan.pdf - Elephant Care ...

Nepal Elephant TB Control and Mgt Action Plan.pdf - Elephant Care ...

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<strong>Nepal</strong> <strong>Elephant</strong> Tuberculosis ulosis<strong>Control</strong> <strong>and</strong>Management agemen<strong>Action</strong> <strong>Plan</strong> (2011-2015)2015)Appendix ISample Drug Dose <strong>and</strong> Cost Calculaons (Based on May 2010 Prices)<strong>TB</strong> drug cost / tablet:Isoniazid (INH); 300 mg = Rs 2Isoniazid-Rifampin combinaon (INH-RIF); 300 mg INH + 600 mg RIF = Rs 8.6Ethambutol (EMB); 800 mg = Rs 6.1The following sample calculaons are for a 3000 kg cow:A. Prophylacc Treatment for Group 2 <strong>Elephant</strong>s: two drugs for nine months1. Oral protocolINH-RIF:Dose /day: 5mg/kg/day x 3000 kg = 15,000 mgTablets/day: 15,000 mg / 300 mg / tablet = 50 tabletsTotal # of tablets: 50 tablets / day X 270 days = 13,500 tabletsTotal cost: 13,500 tablets @ Rs 8.6 /tablet = Rs 116,100 (plus replacements for wasted drugs).2. Rectal protocol (more expensive; use only if oral therapy cannot be managed)INH:Dose /day: 5mg/kg/day x 3000 kg = 15,000 mgTablets/day: 15,000 mg / 300 mg / tablet = 50 tabletsTotal # of tablets: 50 tablets / day X 270 days = 13,500 tabletsTotal cost: 13,500 tablets @ Rs 2 /tablet = Rs 27,000 (plus replacements for wasted drugs).EMB:Dose /day: 30mg/kg/day x 3000 kg = 90,000 mgTablets/day: 90,000 mg / 800 mg / tablet = 112 tabletsTotal # of tablets: 112 tablets / day X 270 days = 30,240 tabletsTotal cost: 30,240 tablets @ Rs 6.1 /tablet = Rs 184,464 (plus replacements for wasted drugs).Total cost: Rs 211,464 (plus replacements for wasted drugs).32

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