Synthetic Strategies for 14C Labelling of Drug Molecules Dr ... - Almac
Synthetic Strategies for 14C Labelling of Drug Molecules Dr ... - Almac
Synthetic Strategies for 14C Labelling of Drug Molecules Dr ... - Almac
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N-Methylation Reduction StepMeOOMeNN +CH 3I/THFNO 2* * *I -NaBH 4/EtOHCH 3MeO NO MeO2OMeOMeNNO 2CH 3Dihydro[ 14 C]isoquinoline [ 14 C]Methiodide Tetrahydro[ 14 C]isoquinolineRadiochemical yield = 77%Bischler-NapieralskiEndocyclic Product
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