Medical Aspects of Chemical Warfare (2008) - The Black Vault

More documents

Recommendations

Info

Riot Control Agents112. Centers for Disease Control. Brief report: illness associated with drift of chloropicrin soil fumigant into a residentialarea—Kern County, California, 2003. MMWR Morb Mortal Wkly Rep. 2004;53:740-742. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5332a4.htm. Accessed November 2, 2005.113. Lee S, McLaughlin R, Harnly M, Gunier R, Kreutzer R. Community exposures to airborne agricultural pesticides inCalifornia: ranking of inhalation risks. Environ Health Perspect. 2002;110:1175–1184.114. Condie LW, Daniel FB, Olson GR, Robinson M. Ten and ninety-day toxicity studies of chloropicrin in Sprague-Dawleyrats. Drug Chem Toxicol. 1994;17:125–137.115. Tamagawa S, Irimajiri T, Oyamada M. Persistence of chloropicrin in soil and environmental effect on it. J Pest Sci(Japan). 1985;10:205–210.116. Buckley LA, Jiang XA, James RA, Morgan KT, Barrow CS. Respiratory tract lesions induced by sensory irritants at theRD50 concentration. Toxicol Appl Pharmacol. 1984;74:417–429.117. Sparks SE, Quistad GB, Casida JE. Chloropicrin: reactions with biological thiols and metabolism in mice. Chem ResToxicol. 1997;10:1001–1007.118. Jackson KE. Chloropicrin. Chem Rev. 1934;14:251–286.119. Mackworth JF. The inhibition of thiol enzymes by lachrymators. Biochem J. 1948;(42) 82–90.120. National Institute for Occupational Safety and Health. Registry of Toxic Effects of Chemical Substances [databaseonline]. Methane, trichloronitro-. Updated 2004. Available at: http://www.setonresourcecenter.com/MSDS_Hazcom/rtecs/pb602160.html. Accessed August 20, 2007.121. DeBaun JR, Miaullis JB, Knarr J, Mihailovski A, Menn JJ. The fate of N-trichloro(14C)methylthio-4-cyclohexene-1,2-dicarboximide((14C)captan) in the rat. Xenobiotica. 1974;4:101–119.122. Alarie Y. Sensory irritation by airborne chemicals. CRC Crit Rev Toxicol. 1973;2:299–363.123. Clayton GD, Clayton FE. Patty’s Industrial Hygiene and Toxicology. New York, NY: John Wiley & Sons; 1981; 2242-2247.124. Amoore JE, Hautala E. Odor as an aid to chemical safety: odor thresholds compared with threshold limit values andvolatilities for 214 industrial chemicals in air and water dilution. J Appl Toxicol. 1983;3(6):272–290.125. Okada E, Takahashi K, Nakamura H. A study of chloropicrin intoxication. Nippon Naika Gakkai Zasshi. 1970;59:1214–1221.126. American Conference of Governmental Industrial Hygienists. Documentation of the Threshold Limit Values and BiologicalExposure Indices. 6th ed. Cincinnati, Ohio: American Conference of Governmental Industrial Hygienists; 1991.127. Graeb C. Berichte des Deutschem Chemisch Gesellschaft LV. Commissionsverlog von R [Report of the German chemical industry].Berlin, Germany: Friedlander and Son; 1881. Available at: http://awr.nti.org/e_researchprofiles/NK/Chemical/1095.html; http://www.nadir.org/nadir/initiativ/sanis/archiv/allergic/kap_01.htm. Accessed on November 2, 2005.128. History of Research and Development of the Chemical Warfare Service Through 1945. Edgewood Arsenal, Md: EdgewoodArsenal Medical Research Laboratory; 1966. EASP 400–427.129. Anderson PJ, Lau GS, Taylor WR, Critchley JA. Acute effects of the potent lacrimator o-chlorobenzylidene malononitrile(CS) tear gas. Hum Exp Toxicol. 1996;15:461–465.130. Castro JA. Effects of alkylating agents on human plasma cholinesterase. Biochem Pharmacol. 1968;17:195-303.131. McNamara, BP, Vocci, FJ, Owens, EJ. The Toxicology of CN. Edgewood Arsenal, Md: Edgewood Arsenal Medical Laboratories;1968. Technical Report 4207.479
Medical Aspects of Chemical Warfare132. Kumar P, Flora SJ, Pant SC, Sachan AS, Saxena SP, Gupta S. Toxicological evaluation of 1-chloroacetophenone anddibenz (b,f)-1,4-oxazepine after repeated inhalation exposure in mice. J Appl Toxicol. 1994;14:411-416.133. Husain K, Kumar P, Malhotra RC. A comparative study of biochemical changes induced by inhalation of aerosols ofo-chloroacetophenone and dibenz (b,f)-1,4-oxazepine in rats. Indian J Med Res. 1991;94:76-79.134. Ballantyne B, Swanston DW. The irritant effects of dilute solutions of dibenzoxazepine (CR) on the eye and tongue.Acta Pharmacol Toxicol (Copenh). 1974;35:412–423.135. Hoffman DH. Eye burns caused by tear gas. Br J Ophthalmol. 1967;51:265-268.136. Leopold IH, Lieberman TW. Chemical injuries of the cornea. Fed Proc. 1971; 30:92-95.137. Macrae WG, Willinsky MD, Basu PK. Corneal injury caused by aerosol irritant projectors. Can J Ophthalmol. 1970;5:3–11.138. Ballantyne B, Gazzard MF, Swanston DW, Williams P. The comparative ophthalmic toxicology of 1-chloroacetophenone(CN) and dibenz (b,f)-1:4-oxazepine(CR). Arch Toxicol. 1975;34:183–201.139. Gaskins JR, Hehir RM, McCaulley DF, Ligon EW Jr. Lacrimating agents (CS and CN) in rats and rabbits. Acute effectson mouth, eyes and skin. Arch Environ Health. 1972;24:449–454.140. Chung CW, Giles AL Jr. Sensitization of guinea pigs to alpha-chloroacetophenone (CN) and ortho-chlorobenzylidenemalononitrile (CS) tear gas chemicals. J Immunol. 1972;109:284–293.141. Holland P, White RG. The cutaneous reactions produced by o-chlorobenzyl-idenemalononitrile and -chloroacetophenonewhen applied directly to the skin of human subjects. Br J Dermatol. 1972;86:150–154.142. Penneys NS, Israel RM, Indgin SM. Contact dermatitis due to 1-chloracetophenone and chemical mace. N Engl J Med.1969;281:413–415.143. National Toxicology Program. TR-379. Toxicology and carcinogenesis studies of 2-chloroacetophenone (CAS No. 532-27-4) in F344/N rats and B6C3F 1mice (inhalation studies). NTP Study Reports [serial online]. 1990;379:1-191. Availableat: http://ntp.niehs.nih.gov/index.cfm?objectid=0709027D-F784-3957-7B0E3F3C05F528AA. Accessed August 21,2007.144. Thorburn KM. Injuries after use of the lachrimatory agent chloroacetophenone in a confined space. Arch Environ Health.1982;37:182–186.145. Stein AA, Kirwan WE. Chloracetophenone (tear gas) poisoning: a clinico-pathologic report. J Forensic Sci. 1964;9:374–382.146. Chapman AJ, White C. Death resulting from lachrimatory agents. J Forensic Sci. 1978;23:527–530.147. Vedder EB, Walton DC. The Medical Aspects of Chemical Warfare. Baltimore, Md: Williams & Wilkins; 1925: 175.148. Kibler AL. The After-Effects of Chloroacetophenone. Edgewood Arsenal, Md: US Department of the Army, Medical ResearchLaboratories; 1933. Technical Report 133.149. Queen FB, Stander T. Allergic dermatitis following exposure to tear gas (chloroacetophenone). JAMA. 1941;117:1879.150. Madden JF. Cutaneous hypersensitivity to tear gas (chloroacetophenone); a case report. AMA Arch Derm Syphilol.1951;63:133–134.151. Levine RA, Stahl CJ. Eye injury caused by tear-gas weapons. Am J Ophthalmol. 1968;65:497–508.152. Rengstorff RH. Tear gas and riot control agents: a review of eye effects. Optom Week. 1969;60:25–28.480
Page 3 and 4:
The Coat of Arms1818Medical Departm
Page 5:
Textbooks of Military MedicinePubli
Page 8 and 9:
MEDICAL ASPECTS o fCHEMICAL WARFARE
Page 10 and 11:
ContentsContributorsForeword by The
Page 12 and 13:
ContributorsMICHAEL ADLER, PhDResea
Page 14 and 15:
DONALD M. MAXWELL, MSResearch Chemi
Page 16 and 17:
ForewordThe US military has been co
Page 18 and 19:
PrefaceA significant concern for th
Page 20:
PrologueThe original edition of Med
Page 23 and 24:
xxii
Page 25 and 26:
Medical Aspects of Chemical Warfare
Page 27 and 28:
Page 29 and 30:
Page 31 and 32:
Page 33 and 34:
Page 35 and 36:
Page 37 and 38:
Page 39 and 40:
Page 41 and 42:
Page 43 and 44:
Page 45 and 46:
Page 47 and 48:
Page 49 and 50:
Page 51 and 52:
Page 53 and 54:
Page 55 and 56:
Page 57 and 58:
Page 59 and 60:
Page 61 and 62:
Page 63 and 64:
Page 65 and 66:
Page 67 and 68:
Page 69 and 70:
Page 71 and 72:
Page 73 and 74:
Page 75 and 76:
Page 77 and 78:
Page 79 and 80:
Page 81 and 82:
Page 83 and 84:
Page 85 and 86:
Page 87 and 88:
Page 89 and 90:
Page 91 and 92:
Page 93 and 94:
Page 95 and 96:
Page 97 and 98:
Page 99 and 100:
Page 101 and 102:
Page 103 and 104:
Page 105 and 106:
Page 107 and 108:
Page 109 and 110:
Page 111 and 112:
Page 113 and 114:
Page 115 and 116:
Page 117 and 118:
Page 119 and 120:
Page 121 and 122:
Page 123 and 124:
Page 125 and 126:
Page 127 and 128:
Page 129 and 130:
Page 131 and 132:
Page 133 and 134:
Page 135 and 136:
Page 137 and 138:
Page 139 and 140:
Page 141 and 142:
Page 143 and 144:
Page 145 and 146:
Page 147 and 148:
Page 149 and 150:
Page 151 and 152:
Page 153 and 154:
Page 155 and 156:
Page 157 and 158:
Page 159 and 160:
Page 161 and 162:
Page 163 and 164:
Page 165 and 166:
Page 167 and 168:
Page 169 and 170:
Page 171 and 172:
Page 173 and 174:
Page 175 and 176:
Page 178 and 179:
Nerve AgentsChapter 5NERVE AGENTSFR
Page 180 and 181:
Nerve AgentsAbout 10,000 to 30,000
Page 182 and 183:
Nerve Agentsphorofluoridate (DFP) w
Page 184 and 185:
Nerve AgentsFig. 5-2. This schemati
Page 186 and 187:
Nerve AgentsExhibit 5-1 continuedis
Page 188 and 189:
Nerve Agentsactivity but only 15% t
Page 190 and 191:
Nerve AgentsTABLE 5-3CHEMICAL, PHYS
Page 192 and 193:
Nerve AgentsTABLE 5-4EFFECTS OF EXP
Page 194 and 195:
Nerve Agentsaffecting the other eye
Page 196 and 197:
Nerve Agentsmay cause severe rhinor
Page 198 and 199:
Nerve Agentsof jerks and tremor.Cen
Page 200 and 201:
Nerve Agentsand they were decreased
Page 202 and 203:
Nerve Agentsnerve agent toxicity on
Page 204 and 205:
Nerve Agentspatient. Decontaminatio
Page 206 and 207:
Nerve AgentsFig. 5-5. The Mark I ki
Page 208 and 209:
Nerve Agentsadministered intramuscu
Page 210 and 211:
Nerve Agentsthat hydroxamine reacti
Page 212 and 213:
Nerve AgentsOral administration may
Page 214 and 215:
Nerve AgentsTABLE 5-7RECOMMENDED TH
Page 216 and 217:
Nerve Agentsimpairment such as whee
Page 218 and 219:
Nerve Agentssuboptimal, manner. The
Page 220 and 221:
Nerve Agentsthan those who did not.
Page 222 and 223:
Nerve Agentssible for binding nerve
Page 224 and 225:
Nerve Agentsfor comparison was not
Page 226 and 227:
Nerve AgentsTABLE 5-11EFFECTS OF PY
Page 228 and 229:
Nerve Agentstivity of smooth muscle
Page 230 and 231:
Nerve Agents38. Grob D, Lilienthal
Page 232 and 233:
Nerve Agents77. McDonough JH, Shih
Page 234 and 235:
Nerve Agents117. McLeod CG Jr, Sing
Page 236 and 237:
Nerve Agents154. Tryphonas l, Veino
Page 238 and 239:
Nerve Agents193. Funckes AJ. Treatm
Page 240 and 241:
Nerve Agents235. Suzuki T, Morita H
Page 242:
Nerve Agents274. Pellegrini JE, Bak
Page 245 and 246:
Page 247 and 248:
Page 249 and 250:
Page 251 and 252:
Page 253 and 254:
Page 255 and 256:
Page 257 and 258:
Page 259 and 260:
Page 261 and 262:
Page 263 and 264:
Page 265 and 266:
Page 267 and 268:
Page 269 and 270:
Page 271 and 272:
Page 273 and 274:
Page 275 and 276:
Page 277 and 278:
Page 279 and 280:
Page 281 and 282:
Page 283 and 284:
Page 285 and 286:
Page 287 and 288:
Page 289 and 290:
Page 291 and 292:
Page 293 and 294:
Page 295 and 296:
Page 297 and 298:
Page 299 and 300:
Page 301 and 302:
Page 303 and 304:
Page 305 and 306:
Page 307 and 308:
Page 309 and 310:
Page 311 and 312:
Page 313 and 314:
Page 315 and 316:
Page 317 and 318:
Page 319 and 320:
Page 321 and 322:
Page 323 and 324:
Page 325 and 326:
Page 327 and 328:
Page 329 and 330:
Page 331 and 332:
Page 333 and 334:
Page 335 and 336:
Page 337 and 338:
Page 339 and 340:
Page 341 and 342:
Page 343 and 344:
Page 345 and 346:
Page 347 and 348:
Page 349 and 350:
Page 351 and 352:
Page 353 and 354:
Page 355 and 356:
Page 357 and 358:
Page 359 and 360:
Page 361 and 362:
Page 363 and 364:
Page 365 and 366:
Page 367 and 368:
Page 369 and 370:
Page 371 and 372:
Page 373 and 374:
Page 375 and 376:
PROCESSMedical Aspects of Chemical
Page 377 and 378:
Page 379 and 380:
Page 381 and 382:
Page 383 and 384:
Page 385 and 386:
Page 387 and 388:
Page 389 and 390:
Page 391 and 392:
Page 393 and 394:
Page 395 and 396:
Page 397 and 398:
Page 399 and 400:
Page 401 and 402:
Page 403 and 404:
Page 405 and 406:
Page 407 and 408:
Page 409 and 410:
Page 411 and 412:
Page 413 and 414:
Page 415 and 416:
Page 417 and 418:
Page 419 and 420:
Page 421 and 422:
Page 423 and 424:
Page 425 and 426:
Page 427 and 428:
Page 429 and 430:
Page 431 and 432:
Page 433 and 434:
Page 435 and 436:
Page 437 and 438:
Page 439 and 440:
Page 441 and 442:
Page 443 and 444:
Page 445 and 446:
Page 447 and 448:
Page 449 and 450:
Page 451 and 452: Medical Aspects of Chemical Warfare
Page 501: Medical Aspects of Chemical Warfare
Page 534 and 535: Triage of Chemical CasualtiesChapte
Page 536 and 537: Triage of Chemical Casualtiesreceiv
Page 538 and 539: Triage of Chemical Casualtiesentran
Page 540 and 541: Triage of Chemical Casualtiescatego
Page 542 and 543: Triage of Chemical CasualtiesIn a f
Page 544 and 545: Triage of Chemical Casualtiesnose)
Page 546 and 547: Triage of Chemical CasualtiesWith n
Page 548 and 549: Triage of Chemical Casualties14. Sa
Page 550 and 551: Decontamination of Chemical Casualt
Page 552 and 553:
Decontamination of Chemical Casualt
Page 554 and 555:
Page 556 and 557:
Page 558 and 559:
Page 560 and 561:
Page 562 and 563:
Page 564 and 565:
Page 566 and 567:
Page 568 and 569:
Page 570 and 571:
Page 572 and 573:
Page 574 and 575:
Page 576 and 577:
Page 578 and 579:
Page 580:
Page 583 and 584:
Page 585 and 586:
Page 587 and 588:
Page 589 and 590:
Page 591 and 592:
Page 593 and 594:
Page 595 and 596:
Page 597 and 598:
Page 599 and 600:
Page 601 and 602:
Page 603 and 604:
Page 605 and 606:
Page 607 and 608:
Page 609 and 610:
Page 611 and 612:
Page 613 and 614:
Page 615 and 616:
Page 617 and 618:
Page 619 and 620:
Page 621 and 622:
Page 623 and 624:
Page 625 and 626:
Page 627 and 628:
Page 629 and 630:
Page 631 and 632:
Page 633 and 634:
Page 635 and 636:
Page 637 and 638:
Page 639 and 640:
Page 641 and 642:
Page 643 and 644:
Page 645 and 646:
Page 647 and 648:
Page 649 and 650:
Page 651 and 652:
Page 653 and 654:
Page 655 and 656:
Page 657 and 658:
Page 659 and 660:
Page 661 and 662:
Page 663 and 664:
Page 665 and 666:
Page 667 and 668:
Page 669 and 670:
Page 671 and 672:
Page 673 and 674:
Page 675 and 676:
Page 677 and 678:
Page 679 and 680:
Page 681 and 682:
Page 683 and 684:
Page 685 and 686:
Page 687 and 688:
Page 689 and 690:
Page 691 and 692:
Page 693 and 694:
Page 695 and 696:
Page 697 and 698:
Page 699 and 700:
Page 701 and 702:
Page 703 and 704:
Page 705 and 706:
Page 707 and 708:
Page 709 and 710:
Page 711 and 712:
Page 713 and 714:
Page 715 and 716:
Page 717 and 718:
Page 719 and 720:
Page 721 and 722:
Page 723 and 724:
Page 725 and 726:
Page 727 and 728:
Page 729 and 730:
Page 731 and 732:
Page 733 and 734:
Page 735 and 736:
Page 737 and 738:
Page 739 and 740:
Page 741 and 742:
Page 743 and 744:
Page 745 and 746:
Page 747 and 748:
• Analyze using GC-MS with methan
Page 749 and 750:
Page 751 and 752:
Page 753 and 754:
Page 755 and 756:
Page 757 and 758:
Page 759 and 760:
Page 761 and 762:
Page 763 and 764:
Page 765 and 766:
Page 767 and 768:
Page 769 and 770:
Page 771 and 772:
Page 773 and 774:
Page 775 and 776:
Page 777 and 778:
Page 779 and 780:
Page 781 and 782:
Page 783 and 784:
Page 785 and 786:
Page 787 and 788:
Page 789 and 790:
Page 791 and 792:
Page 793 and 794:
Page 795 and 796:
Page 798 and 799:
Abbreviations and AcronymsAbBreviat
Page 800:
Abbreviations and AcronymsPADPRP: p
Page 803 and 804:
Page 805 and 806:
Page 807 and 808:
Page 809 and 810:
Page 811 and 812:
Page 813 and 814:
Page 815 and 816:
Page 817 and 818:
Page 819 and 820:
Page 821 and 822:
Page 823 and 824:
Page 825 and 826:
Page 827 and 828:
Page 829 and 830:
Page 831 and 832:
Page 833 and 834:
Page 835 and 836:
Page 837 and 838:
Page 839 and 840:
Page 841 and 842:
Page 843 and 844:
Page 845:
show all

Medical Aspects of Chemical Warfare (2008) - The Black Vault

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?