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CURRICULUM VITAE Ansgar O. Aasen, MD Ph.D ... - Ous-research.no

CURRICULUM VITAE Ansgar O. Aasen, MD Ph.D ... - Ous-research.no

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<strong>CURRICULUM</strong> <strong>VITAE</strong><strong>Ansgar</strong> O. <strong>Aasen</strong>, M.D. <strong>Ph</strong>.D.Current positionsHead Institute for Surgical Research and Consultant Surgeon, Division of Specialised Medicineand Surgery, Oslo University HospitalProfessor of Medicine University of Oslo, NorwayContact information<strong>Ph</strong>one: +47-23073520. Email address: a.o.aasen@medisin.uio.<strong>no</strong>EducationM.D. degree, December 1972.University of Oslo.<strong>Ph</strong>.D. degree, September 1978, University of Oslo.Clinical experienceResidencies: General Surgery: Ullevaal University Hospital,University of Oslo, 1979 - 1980,1984 – 1985 and Baeum Hospital, Baerum Norway, 1982 - 1984.Clinical Chemistry: Ullevaal University Hospital, University of Oslo, 1980 - 1982.Gastrointestinal Surgery: Ullevaal University Hospital, University of Oslo, 1985 - 1988.Consultant Surgeon, Department of Surgery, Section for Gastrointestinal Surgery,Ullevaal University Hospital, University of Oslo, 1988 - 1990.Since 1990 Consultant Surgeon, Department of Surgery, Section for GastrointestinalSurgery and Transplantation, Rikshospitalet, University of Oslo.Specialist in General Surgery 1986 and Gastrointestinal Surgery 1988.Visiting Surgeon Department of Surgery Krankenhaus der Barmherzigen Brüder andLudwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna,Austria, 2005 to 2006.Research and administrative experienceResearch fellow and Assistant Professor, Institute for Surgical Research, Rikshospitalet,University of Oslo, 1975 - 1979.Research fellow, Department of Surgery, Malmoe General Hospital, University of Lund,Sweden 1977.<strong>Ph</strong>.D. thesis: "Activities and Inhibition of Proteases found in Plasma during EndotoxinShock", University of Oslo 1978.Leader and responsible for Surgical Research Laboratory, Department of Surgery andInstitute for Experimental Medical Research, Ullevaal University Hospital, University ofOslo, 1980 - 1990.Since 1991 Professor of Medicine and Head Institute for Surgical Research,Rikshospitalet, University of Oslo.1994 Chairman of Steering committee European Research Network on Multiple SystemOrgan Failure.1998-2002 Secretary Surgical Infection Society-Europe2000-2002 President Shock Society- Europe.


2002-2003 President Surgical Infection Society- Europe.2005-2006 Visiting Professor Department of Surgery Krankenhaus der BarmherzigenBrüder, and Ludwig Boltzmann Institute for Experimental and Clinical Traumatology,Vienna, Austria.2008-2011 Member and leader “ Vurderingskomité 2 Helse Vest forskningsmidler”.Leader “ Hovedkomité Helse Vest forskningsmidler”.285 publications on Surgical Pathophysiology, Clinical Surgery and Medicine.Guidance for the academic doctor degree: 18 fellows since 1981.Professional societies and activitiesMember of council and Secretary Norwegian Association of Gastroenterology 1986 -1992Member of council Scandinavian Surgical Association, Section for Experimental Surgery 1991-1994.Vice Chairman Executive Committee 3rd United European Gastroenterology Week 1994President Oslo Surgical Society 1994 - 1995Member of Council European Shock Society 1994President Elect European Shock Society 1999Secretary Surgical Infection Society - Europe 1995-2000Member of Council Surgical Infection Society - North America 1995-2000Chairman Local Organizing Committee 12 th Annual Meeting, Surgical Infection Society-Europe1999President of the European Shock Society 2000-2002.President Elect Surgical Infection Society-Europe 2001Chairman Local Organising Committee 10 th Congress of the European Shock Society 2002President Surgical Infection Society-Europe 2002-2003Associated Editor SHOCK 2009-Candidates supervised for the <strong>Ph</strong>.D. DegreeSMITH-ERICHSEN, Nils: Septicemia evaluated by means of chromogenic peptide substrateassays. A retrospective study in man. 1985. Main supervisor.RUUD, Tom E: Intraperitoneal proteolyais in experimental and clinical acute pancreatitis. 1989Main supervisor.ROEISE, Olav: Studies on Endotoxin- and Methylprednisoline-Induced Activation of TheContact and Complement System of Plasma. 1990. Main supervisor.NÆSS,Frode: Modulation of mediator- induced responses in experimental endotoxemia, wirhspecial enphasis on the kallikrein-kinin system. 1992. Main supervisor.SA<strong>MD</strong>AL, Frode: Suction-assisted lipectomy. A clinical and experimental study.1994.Supervisor.BUØ, Laila: Proteolytic mechanisms in tumor spread. Studies on the role of serine proteinases inhuman gastrointestinal cancer. 1996. Main supervisor.KARLSRUD, Tove Sigstad: Human kini<strong>no</strong>gens as multifunctional proteins. Studies focusing ontheir function as cysteine protease inhibitors. 1997. Main supervisor.BJØRNLAND, Kristin : Importance of proteolytic enzymes in tumor cell invasion. 1999. Mainsupervisor.


Wang YY, Dahle MK, Steffensen KR, Reinholt FP, Collins JL, Thiemermann C, <strong>Aasen</strong> AO, Gustafsson JA, Wang JE. Liver Xreceptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alphaproduction and p38 mitogen-activated protein kinase activation in liver macrophages. Shock 32: 548-53, 2009.Reikeras O, Sun J, Wang JE, Foster SJ, Bastian D, <strong>Aasen</strong> AO. Immunmodulation of serum in orthopaedic trauma. J Trauma 67:624-7, 2009Gundersen Y, Ruud TE, Krohn CD, Sveen O, Lyngstadaas SP, <strong>Aasen</strong> AO (2010)Impact of hypertonic saline on the release of selected cytokines after stimulation with LPS or peptidoglycan in ex vivo wholeblood from healthy humans. Shock, 34: 450-4, 2010Wang YY, Ryg U, Dahle MK, Steffensen KR, Thiemermann C, Fhaudry IH, Reinholt FP, Collins JL, Nebb HI, <strong>Aasen</strong> AO,Gustafsson JÅ, Wang JE. Liver X receptor protects against liver injury in sepsis caused by rodent cecal ligation and puncture.Surg Infect (Larchmt) 12 (4); 283-9, 2011Stansic M, Lyngstadaas SP, Pripp AH, <strong>Aasen</strong> AO, Lindegaard KF, Iva<strong>no</strong>vic J, Ilstad E, Konglund A, Sandell T, Ellingsen O,Sahle T. Chemokines as markers of local inflammation and angiogenesis in patients with chronic subdural hematoma: aprospective study. Acta Neurochir154 (1) 113-20, 2011Hviid CVB, Samulin-Erdem J, Kunke D, Ahmed SM, Kjeldsen SF, Wang YY, Attramadal H, <strong>Aasen</strong> AO. The matri-cellularCYR61/CCN1 and CTGF/CCN2 –proteins are regulated in experimentally-induced sepsis with initial multiple organ failure.Innate Immunity accepted, 2011

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