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Andreo Fernando AguiarMyoD, Myogenin and IGF-I mRNA expression. Resistance training during 8 and12 weeks induced a significant (p < 0.05) increase in MyoD and myogenin mRNAexpression in the T8 and T12 groups, compared with C8 and C12 groups, respectively(Fig. 9B and C). Myogenin showed an increase of 44.8% and 37.7% in the T8 and T12groups, compared to C8 and C12 groups, respectively (Fig. 9C). In addition, MyoDincreased in 22.9% and 22.3% in the T8 and T12 groups, compared to their respectivecontrols (Fig. 9B). No statistical (p > 0.05) change was observed in MyoD andmyogenin mRNA expression between C8 and C12 groups (Fig. 9B and C). As for IGF-ImRNA expression, there was a significant (p < 0.05) increase of 30.1% in the T8 groupcompared to C8 group, while no statistical change was observed in T12 group comparedto C12 group. In addition, there were no significant changes in IGF-I mRNA expressionbetween C8 and C12 groups (Fig. 9A)Fig. 9. IGF-I (A), MyoD (B) and myogenin (C) mRNA expression in the plantaris muscle of allexperimental groups: C8, 8 weeks control; T8, 8 weeks trained; C12, 12 weeks control; andT12, 12 weeks trained. Values are means ± SD. n= 8 rats per group. * Significant differencecompared to their respective control at p < 0.05) (ANOVA + Tukey test).61