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Andreo Fernando AguiarConsidering that the body weight may influence the maximal strength, 1RM valueswere normalized by body weight (RM/body weight ratio) (Fig. 5). After 8 and 12 weeksof training there was a significant (p < 0.05) increase in relative 1RM in the T8 e T12groups, while no statistical (p > 0.05) difference was observed in their respective controlgroups (Fig. 5). The relative 1RM in the last week were 36.1% and 57.7% higher in theT8 e T12 groups, compared to C8 e C12 groups, respectively. In addition, the trainingduring 12 weeks promoted an increase (p < 0.05) significant of relative 1RM in the T12group compared to T8 group (Fig. 5).Fig. 5. Repetition maximum (1RM) relative to bodyweight (RM/BW ratio) of all groups before( ) and after ( ) of resistance training. The measurements were undertaken on the first day ofthe first week following the 2 weeks adaptation period and on the last day of training. C8, 8weeks control; T8, 8 weeks trained; C12, 12 weeks control; and T12, 12 weeks trained. Valuesare means ± SD. n= 8 rats per group. * Significant difference of T8 and T12 groups compared tovalues obtained in their respective controls at level of p < 0.05; # Significant difference betweenT8 and T12 groups at p < 0.05 (ANOVA + Tukey test).Muscle fiber cross-sectional area (CSA) and muscle weight. A representativeHematoxylin and Eosin (HE) staining used to measure the muscle fiber cross-sectionalarea (CSA) is shown in Fig. 6A-D and the corresponding data are presented in Figure6E. After 8 and 12 weeks of the training there was a significant (p < 0.05) increase inmuscle fiber CSA in the T8 and T12 groups, compared to C8 and C12 groups,respectively (Fig. 6E). In fact, there was a gradual increase in plantaris muscle fibersCSA throughout the training period. A direct statistical comparison revealed a55