N OCIETY' - the Society for Reproductive Biology

Monday 27 th September (cont.)SESSION 6:Founders LectureTime: 12.00 - 1.00 pmVenue: Ballroom 2 + 3Chair: Marilyn RenfreeProfessor Ian WilmutRoslin Institute, EdinburghSESSION 7:Monday 27 th September(cont.)Symposium: From Gamete to Embryo - New HorizonsTime: 2.00-4.00 pm Venue: Ballroom 3Chair: Ian Wilmut"Cloning in biology and medicine"Time Format Page Authors Title2.00 0 65 JMCummins Mitochondrial DNA: our alternativegenome2.40 0 66 IPHearn Primate stem cellsProfessor Wilmut obtained a B.Sc. in Agricultural Science at the University of Nottingham before studyingwith Professor "Chris" Polge FRS at the University of Cambridge. His Ph.D. degree was awarded in 1971 forresearch on the Deep Freeze Preservation of Boar Semen. Subsequent research in Cambridge led to the birthof the first calf from a frozen embryo - "Frosty" - in 1973.3.20 0 67 B Reubinoff, M Pera, C Human embryonic stem cellsFong, AO TrounsonHe moved to Edinburgh in 1973. Initially, studies at Animal Breeding Research Organisation were focused ondevelopmental and physiological studies of prenatal mortality in sheep and pigs. Subsequent research wasconcerned with developing techniques of multiple ovulation/embryo transfer (MOET) in sheep and cattle.This research established the procedures, which are now exploited by PPL Therapeutics at Roslin, for theproduction of proteins needed to treat human disease in the milk of farm animals.Over the past nine years, research has been focused on the factors regulating embryo development after nucleartransfer. This work led to the first birth of live lambs from embryo-derived cells and then to the birth of lambsderived from foetal and adult cells, including Dolly. Recently, genetic changes were introduced into sheep bynuclear transfer from cultured modified cells.As well as being Principal Investigator in Roslin Institute he also serves as Chief Scientific Officer of GeronBio-Med. The objectives of the current research are to develop biomedical applications of the nuclear transferprocedure. These include the provision of organs for xenotransplantation, the derivation of human cells fortherapy and the cloning and modification of animals in agriculture.This symposium is sponsored by:rfdReproduction, Fertility and Development1819