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Measles, Mumps, and Rubella - Centers for Disease Control and ...

Measles, Mumps, and Rubella - Centers for Disease Control and ...

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Vol. 47 / No. RR-8 MMWR 17Women of Childbearing AgeMMR vaccine should be offered to all women of childbearing age (i.e., adolescentgirls <strong>and</strong> premenopausal adult women) who do not have acceptable evidence ofrubella immunity whenever they make contact with the health-care system. Opportunitiesto vaccinate susceptible women include occasions when their children undergoroutine examinations or vaccinations. The continuing occurrence of rubella amongwomen of childbearing age indicates the need to continue vaccination of susceptibleadolescent <strong>and</strong> adult women of childbearing age, <strong>and</strong> the absence of evidence of vaccineteratogenicity indicates that the practice is safe (102 ). Vaccination of susceptiblewomen of childbearing age should• be part of routine general medical <strong>and</strong> gynecologic outpatient care;• take place in all family-planning settings; <strong>and</strong>• be provided routinely be<strong>for</strong>e discharge from any hospital, birthing center, orother medical facility, unless a specific contraindication exists (see Precautions<strong>and</strong> Contraindications).Outbreaks of rubella in the United States recently have occurred among women ofHispanic ethnicity, many of whom were born outside the fifty states. Ef<strong>for</strong>ts should bemade to ensure that all susceptible women of childbearing age, especially those whogrew up outside the fifty states in areas where routine rubella vaccination may notoccur, are vaccinated with MMR vaccine or have other acceptable evidence of immunity(Table 1). Ascertainment of rubella-immune status of women of childbearing age<strong>and</strong> the availability of rubella vaccination should be components of the health-careprogram in places where the risks <strong>for</strong> disease exposure <strong>and</strong> transmission are substantial(e.g., day care facilities, schools, colleges, jails, <strong>and</strong> prisons).No evidence indicates that administration of rubella-containing vaccine virus to apregnant woman presents a risk <strong>for</strong> her fetus, although such a risk cannot be excludedon theoretical grounds. There<strong>for</strong>e, women of childbearing age should receive rubellacontainingvaccines (i.e., rubella, MR, or MMR vaccine) only if they state that they arenot pregnant <strong>and</strong> only if they are counseled not to become pregnant <strong>for</strong> 3 months aftervaccination. Because of the importance of protecting women of childbearing ageagainst rubella, reasonable practices in any immunization program include a) askingwomen if they are pregnant, b) not vaccinating women who state that they are pregnant,c) explaining the potential risk <strong>for</strong> the fetus to women who state that they are notpregnant, <strong>and</strong> d) counseling women who are vaccinated not to become pregnant duringthe 3 months following MMR vaccination.Routine Vaccination of Women Who Are Not Pregnant. Women of childbearing agewho do not have documentation of rubella vaccination or serologic evidence of rubellaimmunity should be vaccinated with MMR, if they have no contraindications tothe vaccine. Birth be<strong>for</strong>e 1957 is not acceptable evidence of immunity <strong>for</strong> women whocould become pregnant (Table 1). The use of MMR vaccine provides the potential additionalbenefit of protection against measles <strong>and</strong> mumps. Serologic testing be<strong>for</strong>evaccination is not necessary <strong>and</strong> might present a barrier to timely vaccination. Routinetesting <strong>for</strong> rubella antibody during clinic visits <strong>for</strong> routine health care, premarital

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