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VIRAL INFECTION53_1slide.pdf

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pathogenesisInitial infection in skin or mucous membranetravel along sensory nerve ending and retrograde axonalflow to neuron in dorsal root ganglia (latent infection)reactivate of latent infected neuron (eg(eg. . stress, fever, UV)newly replicated virus is transported anterograde to a site ator near portal of entry into body causing localized vesicles

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