VIRAL INFECTION53_1slide.pdf
VIRAL INFECTION53_1slide.pdf
VIRAL INFECTION53_1slide.pdf
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pathogenesisPoliovirus infects oropharynx secreted in saliva andswallowMultiplies in intestinal mucosa and lymph nodesHematogenous spreadingInvade to CNS and repilcate in spinal cord (spinal(poliomyelitis), or brain stem (bulbar poliomyelitis)* Virus destroys motor neuron in anterior horn ofspinal cord or brain stem*