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11/22/2011การที่มีน้ําในชองทอง/AscitesFigure 18-4 The major clinical consequences of portal hypertension in the setting of cirrhosis, shown for the male. In women, oligomenorrhea, amenorrhea, and sterilityare frequent, owing to hypogonadism.Downloaded from: Robbins & Cotran Pathologic Basis of Disease (on 11 December 2006 12:34 PM)© 2005 ElsevierThe pathogenesis of ascites• Sinusoidal hypertension และ hypoalbuminemia driving fluid intothe space of Disse and Then removed by hepatic lymphatics.• Percolation of hepatic lymph into the peritoneal cavity: Withcirrhosis, hepatic lymphatic flow may approach 20 L/day,exceeding thoracic duct capacity• Intestinal fluid leakage• Renal retention of sodium and water due to secondaryhyperaldosteronismเสนเลือดขอดโปงพองจากการสองกลองทางเดินอาหารEsophagus varices25