Drs. Colin Jack, Lloyd Skuba and David Zaparinuk - Canadian ...

More documents

Recommendations

Info

ecommends a common sense approach to the selection of restorative materials, whereby patients discuss their specific circumstances with their dentist and choose the most appropriate material for a particular application. CDA is committed to health promotion and the protection of the environment and is working with both government and the dental profession to do so. Dr. Euan Swan Manager, Dental Programs Canadian Dental Association Tooth Regeneration — An Alternative to Implants in the Future came across a radiograph of a pa- I tient with cleidocranial dysostosis who had 84 teeth (Fig. 1), and it made me wonder whether scientists can regenerate teeth. Will patients ever have the option of getting a natural tooth as a replacement instead of an implant or a denture? Figure 1: This patient with cleidocranial dysostosis has 84 teeth. Perhaps this will be a possibility one day. With the success of the human genome project and the identification of almost 300 genes that are responsible for tooth development, 1 scientists may be able to regenerate teeth. If specific genes are manipulated at their target sites, then they could actually regulate the epithelial mesenchymal interactions and initiate odontogenesis on demand. The question that comes to mind is: will the human jaw be able ––– Letters ––– to support new teeth? I believe so, if jaws can support 84 teeth. In cleidocranial dysostosis, loss of heterozygocity of transcription factor Runx 2 may be responsible for the development of supernumerary teeth as part of the third dentition. 1,2 What we need to learn is how to modify expression of these genes and transcription factors to regulate tooth regeneration. Some stem cell researchers think tooth regeneration can be a possibility, and initial results suggest that roots can be regenerated (although obtaining exact crown morphology may be difficult). If we can shape metal crowns with computer-aided design and manufacturing (CAD– CAM), then why not a natural tooth? Who would have thought of cloning or tissue culture a century ago? It’s a reality now. Perhaps in future dentists will be able to replace a missing tooth with a natural tooth and will not depend only on metal implants and dentures. Dr. Ajit Auluck Mangalore, India References 1. Thesleff I. The genetic basis of tooth development and dental defects. Am J Med Genet A 2006; 140(23):2530–5. 2. Jensen BL, Kreiborg S. Development of the dentition in cleidocranial dysplasia. J Oral Pathol Med 1990; 19(2):89–93. Commentary from Dr. Sándor At first glance many readers might simply react to Dr. Auluck’s letter by saying, “I have seen tooth transplantation come and go and tooth regeneration is so many years away that it is simply not practical.” In fact there have been great strides and discoveries made in the area of tooth regeneration by leading Finnish scientists such as Professor Irma Thesleff in Helsinki. The gains have been in 2 complementary areas, genetics and stem cell research. The genetic characterization of the complex interactions involved in odontogenesis has provided us with a genetic 374 JCDA • www.cda-adc.ca/jcda • June 2007, Vol. 73, No. 5 • map of the loci of many of these processes. The other area of progress has been in the understanding of the role of stem cells in these processes. While there will be many details to learn and perfect, such as the production of teeth with the right morphology to fit a particular patient and their occlusal relationships, a modifiable blueprint for these processes is emerging. While the art and science of dental implant placement and restoration has emerged as an extremely predictable and reliable part of dental treatment today, the future genetic or stem cell morphing of de novo teeth may offer a viable alternative. Even if these possibilities are all things of the future, it is good for us to dream and inspire science to help create a better future for our patients. Dr. George K.B. Sándor Professor of oral and maxillofacial surgery and clinical director Graduate training program in oral and maxillofacial surgery and anesthesia University of Toronto and Mount Sinai Hospital Toronto, Ontario
For more on A-dec 500, contact your authorized A-dec dealer, visit a-dec.com, or call 1-800-547-1883 today. ©2007 A-dec ® Inc. All rights reserved. www.a-dec.com Worksurface and instrument holders that rotate and pivot for practically unlimited positioning Unique track-mount for maximum flexibility in monitor positioning Sturdy, round worksurface with enough room to hold precisely what you need A-DEC 500 ® Productivity at 12 O’Clock Better positioning is paramount to productive dentistry, no matter what delivery style you choose. Which is why we created A-dec 500 at 12 o’clock. In addition to a round, rotating, and height-adjustable worksurface, A-dec 500 features pivoting instrument holders that position virtually anywhere around the worksurface—which means better visibility, less stretching, and reduced motion for you and your assistant. Add the ability to seamlessly integrate electric motors, intraoral cameras, as well as other small equipment, and you have a completely flexible system that offers better ergonomics and efficiency than any other 12 o’clock delivery solution available today.
Page 1 and 2: PM40064661 R09961 JOURNAL OF THE CA
Page 3 and 4: CDA Executive Director George Weber
Page 5 and 6: c o n t E n t s JCDA JOURNAL OF THE
Page 7 and 8: 417 c o n t E n t s All matters per
Page 9 and 10: Dr. John P. O’Keefe “Thomson Sc
Page 11: Dr. Darryl Smith “Your success in
Page 16 and 17: Want to make your practice stand ou
Page 18 and 19: --- News & Updates --- New CDA Memb
Page 20 and 21: --- News & Updates --- AHA Updates
Page 22 and 23: --- News & Updates --- AAOMS Positi
Page 24 and 25: 5 th Annual CELEBRATING SMILES GALA
Page 26 and 27: Mr. Joel Neal and Dr. Wayne Halstro
Page 28 and 29: Dr. Deborah Stymiest, CDA vice-pres
Page 30 and 31: Introducing a New Staff Savings Pla
Page 32 and 33: Over the past 50 years our family h
Page 34 and 35: Q u E S T I o N 2 ------- Point of
Page 36: Q u E S T I o N 3 ------- Point of
Page 39: Table 1 Methods of oxygen delivery
Page 42 and 43: --- Epstein --- Table 1 Guidelines
Page 44 and 45: --- Epstein --- Table 4 Recommendat
Page 46 and 47: GUM® Adult Toothbrushes… The Den
Page 48 and 49: “Oral Sedation Dentistry” North
Page 50 and 51: of dental malpractice (negligence)
Page 52 and 53: Figure 2: An image made on a photos
Page 54 and 55: 30. Kalpidis CD, Setayesh RM. Hemor
Page 56 and 57: B O N D , F I L L A N D C U R E 4 M
Page 58 and 59: Figure 1a: Lateral view of 55-year-
Page 60 and 61: Figure 2a: Panoramic radiograph of
Page 62 and 63: patients to a specialist for even t
Page 64 and 65:
CAVITIES | GINGIVITIS | PLAQUE | SE
Page 66 and 67:
Figure 1: Orthopantomogram, taken w
Page 68 and 69:
2. Restoration of the spaces with a
Page 70 and 71:
��
Page 72 and 73:
elatively rare, few large case seri
Page 74 and 75:
Conclusion Oral lipomas are relativ
Page 76 and 77:
Three things dentists have in commo
Page 78 and 79:
Over the years, the senior author (
Page 80 and 81:
Focusing detailed attention specifi
Page 82 and 83:
C L A S S I F I E D A D S sharing s
Page 84 and 85:
C L A S S I F I E D A D S FACULTY P
Page 86 and 87:
C L A S S I F I E D A D S purchase
Page 88 and 89:
C L A S S I F I E D A D S YUKON - W
Page 90 and 91:
C a n a d i a n d en t i s t s’ i
Page 92:
��
show all

Drs. Colin Jack, Lloyd Skuba and David Zaparinuk - Canadian ...

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?