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martin-benson - Royal Marsden Hospital

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The <strong>Royal</strong> <strong>Marsden</strong>Open gastroscopy – Barrett’sColumnar-linedoesophagus (Barrett’s)• Risk developing adenoCa – OR 44• Small absolute increase individual risk(1 cancer per 1000pts pa)• 40% pts adenoCa – no reflux symptoms• CLO incidence – 5-15% symptomatic pts• Endoscopic screening – chronic symptoms,>50 years• Surveillance: adenoCa -1/100 pt years F/U• No RCT to support• Observational studies – increased number ofearly tumours and increased survival

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