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martin-benson - Royal Marsden Hospital

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The <strong>Royal</strong> <strong>Marsden</strong>Dyspepsia - Discriminatory value ofsymptoms• Suspicion of organic disease increased by presence of certainsymptoms* GORD:Heartburn, positional component, relief with antacids(Horrocks and deDombal ‘78)• Unaided clinical diagnosis (in absence of alarm symptoms):limited value• * 50% active PUD missed by clinical diagnosis• * 33% organic causes incorrectly diagnosed as functional(Byzer ‘91)

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