12.07.2015 Views

Dynamical Systems in Neuroscience:

Dynamical Systems in Neuroscience:

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Electrophysiology of Neurons 53+50 mV-10 mV 10 ms-40 mV-60 mV-80 mV-100 mV-20 mV Figure 2.24: Multiple voltage steps are oftenneeded to determ<strong>in</strong>e time constants of<strong>in</strong>activation; see Ex. 7.9. [M.S.] Modify the MATLAB program from Ex. 6 to handle multiple currents.10. [M.S.] Add a PDE solver to the MATLAB program from exercise 6 to simulatepoor space and voltage clamp conditions.11. [Ph.D.] Introduce numerical optimization <strong>in</strong>to the dynamic clamp protocol toanalyze experimentally <strong>in</strong> real time the (<strong>in</strong>)activation parameters of membranecurrents.12. [Ph.D.] Use new classification of families of channels (Kv3,1, Na v 1.2, etc. seeHille 2001), determ<strong>in</strong>e the k<strong>in</strong>etics of each subgroup, and provide a completetable similar to those <strong>in</strong> Sect. 2.3.5.

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