12.07.2015 Views

Dynamical Systems in Neuroscience:

Dynamical Systems in Neuroscience:

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332 Simple Modelsrat RTN neuronsimple modeltonic mode burst mode tonic mode burst mode200 ms-65 mV-85 mVFigure 8.32: Comparison of <strong>in</strong> vitro record<strong>in</strong>gs of a reticular thalamic nucleus (RTN)neuron of a rat with simulations of the simple model 40 ˙v = 0.25(v +65)(v +45)−u+I,˙u = 0.015{b(v + 65) − u}, b = 10 if v ≤ −65 and b = 2 otherwise. When v ≥ 0 (spikecutoff), then v ← −55, u ← u + 50. Injected current pulses are 50, 70, 110 pA. Inburst mode, the cell was hyperpolarized to −80 mV prior to <strong>in</strong>ject<strong>in</strong>g a depolariz<strong>in</strong>gpulse of current (data provided S.H. Lee and C.L. Cox).

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