2006 The top 800 UK & 1250 Global companies by R&D investment

Ranking of the top 1250 global companies by R&D investment by country within region–––––––––––––––––– 2005/06 R&D investment –––––––––––––––––– ——–—–– Operating profit ——–—–– ––––––––––––––––– Sales and employees ––––––––––––––––– ————––—–––—— R&D and employees ——–—––——––––—–––––––––– Sales –––––––––– ––––– Sales / employee ––––– ––––––––– Employees ––––––––– ––––– R&D / employee ––––– Sales––––– Growth ––––– operating R&D + ––––– Growth ––––– ––––– Growth ––––– –––––– Growth ––––– ––––– Growth ––––– –––––– Growth ––––– outside –––Market cap –––change change profit sales capex as change change sales change change change change change change change change region changeCompany £m 1 yr % 4 yr % % % % sales £m 1 yr % 4 yr % % £m 1 yr % 4 yr % £000 1 yr % 4 yr % number 1 yr % 4 yr % £000 1 yr % 4 yr % % £m %1.5 USA continuedAMIS 50.91 13 45 269.8 17.4 24.2 19 -62 -14 6.4 293 -3 23 104.2 -11 n/a 2816 9 n/a 18.1 4 n/a 58 467 -18PerkinElmer 50.89 0 3 53.9 5.1 6.6 94 -8 126 9.6 989 1 12 123.6 26 45 8000 -20 -23 6.4 25 34 66 1354 -12Idenix Pharmaceuticals 50.26 8 62 n/m 133.3 143.5 -33 n/m n/m -86.3 38 -32 51 172.9 -61 n/a 218 74 n/a 230.6 -38 n/a n/a 292 n/aAvery Dennison 49.74 4 13 24.6 1.6 4.5 203 -19 -16 6.4 3188 2 21 141.1 -3 7 22600 6 14 2.2 -2 -1 58 3793 5Trimble Navigation 49.09 9 25 67.3 10.9 13.9 73 58 223 16.2 451 16 44 183.3 2 24 2462 14 16 19.9 -5 8 n/a 1544 36Thq 49.07 15 99 247.4 10.4 13.3 20 -54 -30 4.2 470 7 43 293.6 -13 -24 1600 23 86 30.7 -6 11 n/a 917 8InterMune 48.19 2 -14 n/m 56.3 57.8 -24 n/m n/m -27.8 86 -3 29 443.3 64 80 193 -41 -26 249.7 72 16 n/a 302 6CheckFree 48.08 25 36 128.7 10.9 15.4 37 234 n/a 8.5 441 25 46 144.7 23 37 3050 2 5 15.8 22 29 n/a 1965 -4Varian Medical Systems 47.80 14 47 26.9 5.9 9.1 178 19 77 22.1 805 12 41 223.7 2 14 3600 10 25 13.3 4 19 49 3790 26Fair Isaac 47.35 14 57 41.9 10.2 12.2 113 10 65 24.3 465 13 55 166.4 24 29 2796 -9 21 16.9 25 32 n/a 1319 -11Praxair 46.60 4 11 6.1 1.0 12.5 758 17 44 17.0 4459 16 36 163.3 15 27 27306 1 7 1.7 3 4 n/a 10361 7Emulex 46.58 9 53 77.7 21.3 25.7 60 n/a n/a 27.4 219 3 28 414.4 2 -4 528 1 33 88.2 8 17 45 740 -21Biomet 46.42 23 49 14.5 4.2 9.4 321 11 36 29.3 1095 16 44 182.5 3 14 6000 13 20 7.7 9 17 34 4813 -13Valspar 46.18 4 18 29.3 2.9 5.2 157 0 19 10.0 1581 11 24 209.7 11 17 7540 1 7 6.1 4 10 n/a 1489 2Amylin Pharmaceuticals 45.65 -8 12 n/m 55.8 76.9 -122 n/m n/m -149.0 82 310 321 71.2 114 91 1150 92 171 39.7 -52 -62 n/a 3425 183Affymetrix 45.38 5 13 136.9 21.2 32.1 33 -5 433 15.5 214 6 27 194.5 -12 2 1101 21 24 41.2 -13 -8 48 787 -54Varian Semiconductor Equipment 45.24 15 35 88.2 12.9 15.0 51 3 93 14.7 350 13 29 230.4 8 24 1518 5 6 29.8 9 27 78 1052 13Fairchild Semiconductor 45.20 -5 -4 n/m 5.4 12.3 -3 -104 -110 -0.3 830 -11 -2 93.0 -10 5 8929 -1 -7 5.1 -4 3 90 1151 1Convergys 44.79 -1 -23 32.8 3.0 8.1 137 28 -5 9.1 1504 4 10 22.9 5 -10 65700 -1 21 0.7 0 -39 n/a 1556 35FileNET 44.36 -3 3 161.4 18.1 20.7 27 68 704 11.2 246 6 17 145.0 1 17 1695 5 0 26.2 -8 3 30 850 23Sigmatel 44.24 126 284 134.7 23.4 28.1 33 6 436 17.4 189 67 270 309.8 -35 n/a 610 156 n/a 72.5 -12 n/a n/a 91 n/aSealed Air 44.15 4 18 14.6 1.9 4.2 303 9 101 12.7 2379 8 20 140.0 11 25 17000 -3 -4 2.6 7 23 48 2361 -8King Pharmaceuticals 43.11 9 68 42.6 4.2 7.2 101 n/a 20 9.8 1034 36 49 369.9 34 38 2795 1 8 15.4 8 59 n/a 2411 25Enterasys Networks 42.99 -12 -30 n/m 20.7 23.1 -51 n/m n/m -24.4 208 -14 -42 180.8 5 14 1150 -18 -50 37.4 7 30 52 n/l n/lMercury Interactive(now part of Hewlett-Packard) 42.94 32 80 83.0 10.8 15.5 52 94 73 13.0 399 35 74 150.2 18 17 2659 15 49 16.2 15 22 40 n/l n/lAmerican Axle & Manufacturing 42.87 7 25 68.7 2.2 11.2 62 -59 -64 3.2 1973 -6 -2 179.4 -7 3 11000 1 -6 3.9 6 32 22 503 -39Smith International 42.87 10 31 11.0 1.3 4.5 391 53 92 12.0 3250 26 51 221.1 14 24 14697 11 23 2.9 -1 7 n/a 5520 31Tibco Software 42.60 20 1 125.7 16.4 19.8 34 -14 n/a 13.1 260 15 44 172.6 4 2 1505 11 40 28.3 8 -30 n/a 1234 38Estee Lauder 42.11 8 15 10.0 1.1 4.8 420 18 50 11.4 3691 9 25 155.7 3 9 23700 7 15 1.8 1 0 n/a 4647 59Eclipsys 41.90 -2 16 n/m 18.8 23.8 -2 n/m n/m -0.7 223 24 50 110.5 22 25 2020 2 19 20.7 -4 -2 1 433 -8ImClone Systems 41.88 24 -22 107.7 18.7 40.7 39 -47 n/a 17.4 223 -1 173 225.5 -14 96 991 14 69 42.3 8 -59 n/a 1648 7ADC Telecommunications 41.71 21 -54 99.7 6.1 8.6 42 524 n/a 6.1 686 50 -6 83.7 37 -1 8200 9 0 5.1 11 -52 n/a 835 -48Cooper Industries 41.65 1 17 12.8 1.5 3.6 326 13 50 11.8 2755 6 13 95.3 -1 10 28903 8 2 1.4 -6 14 n/a 4660 34Mindspeed Technologies 41.56 -10 n/a n/m 63.8 67.4 -35 n/m n/a -54.1 65 -6 n/a 124.3 13 n/a 524 -17 n/a 79.3 8 n/a 71 96 7JohnsonDiversey 41.36 -6 13 61.2 2.1 4.4 68 -24 -7 3.5 1928 4 41 160.7 4 n/a 12000 0 n/a 3.4 -6 n/a n/a n/l n/lAxcelis Technologies 41.30 12 3 n/m 19.0 21.1 0 -101 n/m -0.2 217 -27 -1 142.1 -23 10 1527 -4 -11 27.0 17 16 n/a 327 -10MGI PHARMA 41.29 13 57 n/m 25.4 26.3 -78 n/m n/m -47.8 163 43 265 283.0 -30 51 575 104 175 71.8 -44 -43 n/a 656 -40Realnetworks 41.20 36 38 17.0 21.8 26.0 242 n/a n/a 127.7 189 22 55 202.9 7 27 933 14 22 44.2 19 13 n/a 965 86Intergraph 40.81 1 6 40.4 12.1 13.5 101 -24 -7 30.1 336 5 9 97.4 6 20 3450 -1 -10 11.8 3 16 51 606 -9Nektar Therapeutics 40.81 58 13 n/m 55.5 69.7 -107 n/m n/m -145.6 74 11 29 94.7 -6 12 777 17 15 52.5 35 -2 n/a 578 -1Energizer 40.72 -6 34 15.6 2.3 5.8 261 15 73 15.0 1741 6 41 117.3 -7 11 14848 15 19 2.7 -18 9 n/a 2138 -17Cell Therapeutics 40.06 -32 -6 n/m 427.3 439.9 -79 n/m n/m -841.3 9 -46 -17 43.8 2 33 214 -47 -34 187.2 28 45 29 76 -24Cytec Industries 39.90 71 94 55.5 2.3 5.9 72 -32 -12 4.2 1704 70 97 233.4 5 20 7300 62 65 5.5 6 18 54 1477 n/aEcolab 39.83 11 38 12.6 1.5 7.4 316 2 25 12.0 2641 8 32 117.9 3 22 22400 5 9 1.8 6 27 n/a 6371 27Polaris Industries 39.69 12 41 32.2 3.6 8.4 123 22 35 11.3 1089 5 17 302.5 5 14 3600 0 2 11.0 12 37 n/a 922 -31Waters 38.97 3 19 23.9 5.8 5.8 163 -1 34 24.2 675 5 22 149.9 -2 3 4500 7 18 8.7 -4 1 65 2451 -18Nabi Biopharmaceuticals 38.93 10 112 n/m 61.9 69.9 -76 n/m n/m -120.6 63 -40 -45 81.1 -44 -52 776 7 12 50.2 3 93 15 180 -63IDX Systems(now part of General Electric) 38.88 20 32 152.4 12.8 17.5 26 45 856 8.4 303 30 32 125.9 11 89 2409 18 -38 16.1 2 84 18 n/l n/lUnova (now Intermec) 38.74 7 12 151.9 6.1 7.0 25 n/a >999 4.0 640 35 -8 256.4 142 103 2497 -44 -54 15.5 91 138 56 1083 10LTX 38.62 -2 -2 n/m 49.3 57.9 -76 >-999 n/m -97.5 78 -47 -35 165.7 -29 -2 473 -26 -33 81.6 32 43 n/a 192 -6Millipore 38.47 6 21 46.9 6.7 15.4 82 2 24 14.2 577 12 30 120.3 5 17 4800 7 11 8.0 -1 9 64 1998 9Fortune Brands 38.39 -4 11 5.7 0.8 3.6 670 -2 31 14.3 4674 10 31 154.3 15 29 30298 -5 -1 1.3 1 9 n/a 6212 -20L-3 Communications 38.27 -8 -1 6.7 0.7 2.0 575 32 98 10.5 5501 37 106 92.5 2 n/a 59500 35 n/a 0.6 -31 n/a 10 5079 -4Medicis Pharmaceutical 38.26 298 203 66.8 17.4 18.2 57 -6 32 26.1 220 24 62 611.5 10 23 359 13 31 106.6 254 117 n/a 615 n/aBE Aerospace 38.21 19 42 70.1 7.8 9.8 55 45 >999 11.1 492 15 28 123.5 1 17 3980 14 9 9.6 5 30 53 1069 90Wind River Systems 38.18 8 -7 287.7 24.6 27.3 13 125 n/a 8.6 155 13 2 132.5 7 19 1171 5 -15 32.6 3 8 45 420 -46Newmarket 38.09 0 14 91.0 6.1 7.7 42 14 658 6.7 626 20 42 556.4 21 40 1126 -1 2 33.8 1 12 54 533 234ICOS 37.92 17 1 n/m 91.2 98.1 -43 n/m n/m -104.0 42 -4 -13 59.4 -8 -30 700 4 19 54.2 13 -17 n/a 896 0Medicines 37.51 31 65 n/m 42.9 45.1 -7 -177 n/m -8.0 87 4 113 318.2 -17 50 275 25 55 136.4 5 6 n/a 615 -3Avon Products 37.40 1 24 5.6 0.8 3.3 672 -3 21 14.2 4747 5 22 96.9 2 14 49000 3 7 0.8 -2 15 n/a 7174 -19Cymer 37.29 10 4 157.4 16.7 21.6 24 -34 173 10.6 223 -8 23 254.2 -20 11 879 14 10 42.4 -4 -6 n/a 892 31Encysive Pharmaceuticals 36.99 12 132 n/m 453.4 468.2 -45 n/m n/m -555.4 8 2 25 37.1 -46 -40 220 88 108 168.1 -40 13 n/a 146 -64Analogic 36.75 8 24 165.7 17.3 20.3 22 454 57 10.4 212 3 -3 123.1 1 1 1725 1 -4 21.3 6 28 45 377 -4138 The 2006 R&D ScoreboardThe 2006 R&D Scoreboard 139