Estrogen Receptor Null Mice - Endocrine Reviews

More documents

Recommendations

Info

June, 1999 ESTROGEN RECEPTOR NULL MICE 409 123. Couse JF, Curtis SW, Washburn TF, Lindzey J, Golding TS, Lubahn DB, Smithies O, Korach KS 1995 Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene. Mol Endocrinol 9:1441–1454 124. Luetteke NC, Qiu TH, Peiffer RL, Oliver P, Smithies O, Lee DC 1993 TGF� deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice. Cell 73:263–278 125. Dietz HC, Valle D, Francomano CA, Kendzior Jr RJ, Pyeritz RE, Cutting GR 1993 The skipping of constitutive exons in vivo induced by nonsense mutations. Science 259:680–683 126. Wakamatsu N, Kobayashi H, Miyatake T, Tsuji S 1992 A novel exon mutation in the human �-hexosaminidase � subunit gene affects 3� splice site selection. J Biol Chem 267:2406–2413 127. Reed R, Maniatis T 1986 A role for exon sequences and splice-site proximity in splice-site selection. Cell 46:681–690 128. Nelson RJ, Young KA 1998 Behavior in mice with targeted disruption of single genes. Neurosci Biobehav Rev 22:453–462 129. Crawley JN, Paylor R 1997 A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice. Horm Behav 31:197–211 130. Gerlai R 1996 Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? [published erratum appears in Trends Neurosci 1996 Jul;19(7):271]. Trends Neurosci 19:177–181 131. Olsen KL 1992 Genetic influences on sexual behavior differentiation. In: Gerall AA, Moltz H, Ward IL (eds) Sexual Differentiation. Plenum Press, New York, pp 1–40 132. Greenman DL, Dooley K, Breeden CR 1977 Strain differences in the response of the mouse to diethylstilbestrol. J Toxicol Environ Health 3:589–597 133. Greenman DL, Delongchamp RR 1979 Variability of response to diethylstilbestrol: a comparison of inbred with hybrid mice. J Toxicol Environ Health 5:131–143 134. Roper RJ, Griffith JS, Lyttle CR, Doerge RW, McNabb AW, Broadbent RE, Teuscher C 1999 Interacting quantitative trait loci control phenotypic variation in murine estradiol-regulated responses. Endocrinology 140:556–561 135. Mani SK, Blaustein JD, O’Malley BW 1997 Progesterone receptor function from a behavioral perspective. Horm Behav 31:244–255 136. Ogasawara Y, Okamoto S, Kitamura Y, Matsumoto K 1983 Proliferative pattern of uterine cells from birth to adulthood in intact, neonatally castrated, and/or adrenalectomized mice, assayed by incorporation of [ 125 I]iododeoxyuridine. Endocrinology 113:582– 587 137. Luo X, Ikeda Y, Parker KL 1994 A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell 77:481–490 138. Parker KL 1998 The roles of steroidogenic factor 1 in endocrine development and function. Mol Cell Endocrinol 145:15–20 139. Horigome T, Ogata F, Golding TS, Korach KS 1988 Estradiolstimulated proteolytic cleavage of the estrogen receptor in mouse uterus. Endocrinology 123:2540–2548 140. Yamashita S, Newbold RR, McLachlan JA, Korach KS 1990 The role of the estrogen receptor in uterine epithelial proliferation and cytodifferentiation in neonatal mice. Endocrinology 127:2456–2463 141. Blaustein JD 1992 Cytoplasmic estrogen receptors in rat brain: immunocytochemical evidence using three antibodies with distinct epitopes. Endocrinology 131:1336–1342 142. Schomberg DW, Couse JF, Mukherykee A, Lubahn DB, Sar M, Mayo KE, Korach KS 1999 Targeted disruption of the estrogen receptor-� (ER�) gene in female mice: characterization of ovarian reponses and phenotype in the adult. Endocrinology 140:2733–2744 143. Cuhna GR, Cooke PS, Bigsby R, Brody JR 1991 Ontogeny of sex steroid receptors in mammals. In: Parker MG (ed) Nuclear Hormone Receptors: Molecular Mechanisms, Cellular Functions, Clinical Abnormalities. Academic Press, London, pp 235–268 144. Yamashita S, Newbold RR, McLachlan JA, Korach KS 1989 Developmental pattern of estrogen receptor expression in female mouse genital tracts. Endocrinology 125:2888–2896 145. Pasqualini JR, Sumida C 1986 Ontogeny of steroid receptors in the reproductive system. Int Rev Cytol 101:275–324 146. Katzenellenbogen BS, Greger NG 1974 Ontogeny of uterine responsiveness to estrogen during early development in the rat. Mol Cell Endocrinol 2:31–42 147. Sheehan DM, Branham WS, Medlock KL, Olson ME, Zehr DR 1981 Uterine responses to estradiol in the neonatal rat. Endocrinology 109:76–82 148. Kraus WL, Katzenellenbogen BS 1993 Regulation of progesterone receptor gene expression and growth in the rat uterus: modulation of estrogen actions by progesterone and sex steroid hormone antagonists. Endocrinology 132:2371–2379 149. Eide A 1975 The effect of oestradiol on the DNA synthesis in neonatal mouse uterus and cervix. Cell Tissue Res 156:551–555 150. Forsberg JG 1975 Late effects in the vaginal and cervical epithelia after injections of diethylstilbestrol into neonatal mice. Am J Obstet Gynecol 121:101–104 151. Martin L 1980 Estrogens, anti-estrogens and the regulation of cell proliferation in the female reproductive tract in vivo. In: McLachlan JA (ed) Estrogens in the Environment. Elsevier North Holland, Inc, New York, pp 103–130 152. Quarmby VE, Korach KS 1984 The influence of 17 �-estradiol on patterns of cell division in the uterus. Endocrinology 114:694–702 153. Korach KS, Couse JF, Curtis SW, Washburn TF, Lindzey J, Kimbro KS, Eddy EM, Migliaccio S, Snedeker SM, Lubahn DB, Schomberg DW, Smith EP 1996 Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes. Recent Prog Horm Res 51:159–186 154. Lindzey J, Curtis SW, Washburn TF, Korach KS 1996 Uterotropic effects of dihydrotestosterone in estrogen receptor knockout and wild type mice. Program of the 78th Annual Meeting of The Endocrine Society, San Francisco, CA, 1996 (Abstract OR18–4), p 77 155. Clark JH, Markaverich BM 1988 Actions of ovarian steroid hormones. In: Knobil E, Neil JD, Ewing LL, Greenwald GS, Markert CL, Pfaff DW (eds) The Physiology of Reproduction. Raven Press, New York, pp 675–724 156. Stancel GM, Blatti P, Benson RH, Gardner RM, Kirkland JL, Ireland JS, Sidikaro J, Weil PA 1979 Hormonal control of uterine growth and regulation of responsiveness to estrogen. In: Hamilton TH, Clark JH, Sadler WA (eds) Ontogeny of Receptors and Reproductive Hormone Action. Raven Press, New York, pp 119–132 157. Korach KS 1994 Insights from the study of animals lacking functional estrogen receptor. Science 266:1524–1527 158. Hardin JW, Markaverich BM, Clark JH, Padykula HA 1979 Estrogenic stimulation of biochemical and morphological differentiation in rat uterine nuclei. In: Hamilton TH, Clark JH, Sadler WA (eds) Ontogeny of Receptors and Reproductive Hormone Action. Raven Press, New York, pp 119–132 159. Kastner P, Krust A, Turcotte B, Stropp U, Tora L, Gronemeyer H, Chambon P 1990 Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J 9:1603–1614 160. Kraus WL, Montano MM, Katzenellenbogen BS 1993 Cloning of the rat progesterone receptor gene 5�-region and identification of two functionally distinct promoters. Mol Endocrinol 7:1603–1616 161. Liu Y, Teng CT 1992 Estrogen response module of the mouse lactoferrin gene contains overlapping chicken ovalbumin upstream promoter transcription factor and estrogen receptor-binding elements. Mol Endocrinol 6:355–364 162. Tibbetts TA, Mendoza-Meneses M, O’Malley BW, Conneely OM 1998 Mutual and intercompartmental regulation of estrogen receptor and progesterone receptor expression in the mouse uterus. Biol Reprod 59:1143–1152 163. DiAugustine RP, Petrusz P, Bell GI, Brown CF, Korach KS, McLachlan JA, Teng CT 1988 Influence of estrogens on mouse uterine epidermal growth factor precursor protein and messenger ribonucleic acid. Endocrinology 122:2355–2363 164. Huet-Hudson YM, Chakraborty C, De SK, Suzuki Y, Andrews GK, Dey SK 1990 Estrogen regulates the synthesis of epidermal growth factor in mouse uterine epithelial cells. Mol Endocrinol 4:510–523 165. Nelson KG, Takahashi T, Lee DC, Luetteke NC, Bossert NL, Ross K, Eitzman BE, McLachlan JA 1992 Transforming growth factor-� is a potential mediator of estrogen action in the mouse uterus. Endocrinology 131:1657–1664 166. Murphy LJ, Ghahary A 1990 Uterine insulin-like growth factor-1:
410 COUSE AND KORACH Vol. 20, No. 3 regulation of expression and its role in estrogen-induced uterine proliferation. Endocr Rev 11:443–453 167. Hom YK, Young P, Wiesen JF, Miettinen PJ, Derynck R, Werb Z, Cunha GR 1998 Uterine and vaginal organ growth requires epidermal growth factor receptor signaling from stroma. Endocrinology 139:913–921 168. Nelson KG, Takahashi T, Bossert NL, Walmer DK, McLachlan JA 1991 Epidermal growth factor replaces estrogen in the stimulation of female genital-tract growth and differentiation. Proc Natl Acad Sci USA 88:21–25 169. Ignar-Trowbridge DM, Nelson KG, Bidwell MC, Curtis SW, Washburn TF, McLachlan JA, Korach KS 1992 Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor. Proc Natl Acad Sci USA 89:4658–4662 170. Curtis SW, Washburn T, Sewall C, DiAugustine R, Lindzey J, Couse JF, Korach KS 1996 Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor. Proc Natl Acad Sci USA 93:12626–12630 171. Cooke PS, Buchanan DL, Young P, Setiawan T, Brody J, Korach KS, Taylor J, Lubahn DB, Cunha GR 1997 Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium. Proc Natl Acad Sci USA 94:6535–6540 172. Buchanan DL, Setiawan T, Lubahn DB, Taylor JA, Kurita T, Cunha GR, Cooke PS 1999 Tissue compartment-specific estrogen receptor-� participation in the mouse uterine epithelial secretory response. Endocrinology 140:484–491 173. Das SK, Taylor JA, Korach KS, Paria BC, Dey SK, Lubahn DB 1997 Estrogenic responses in estrogen receptor-� deficient mice reveal a distinct estrogen signaling pathway. Proc Natl Acad Sci USA 94:12786–12791 174. Ghosh D, Bagenin A, Taylor JA, Lubahn DB, Methoxychlor acts in ER�-KO mice through an ER-� independent mechanism. Program of the 80th Annual Meeting of The Endocrine Society, New Orleans, LA, 1998 (Abstract P1-569), p 236 175. Teng CT, Pentecost BT, Chen YH, Newbold RR, Eddy EM, McLachlan JA 1989 Lactotransferrin gene expression in the mouse uterus and mammary gland. Endocrinology 124:992–999 176. Parvizi N, Ellendorf F, Wuttke W 1981 Catacholestrogens in the brain: action on pituitary hormone secretion and catacholamine turnover. In: Fuxe K, Gustafsson JÅ, Wetterberg L (eds) Steroid Hormone Regulation of the Brain. Pergamon Press, Oxford, New York, p 107 177. Fuchs E, Gliessman P, Hess DL, Pau KY, Spies HG, Wuttke W 1986 Release rates of catecholamines, GABA and �-endorphin in the preoptic area and the mediobasal hypothalamus of the rhesus monkey in push-pull perfusates: correlation with blood hormone levels. Exp Brain Res 65:224–228 178. Spicer LJ, Hammond JM 1989 Regulation of ovarian function by catecholestrogens: current concepts. J Steroid Biochem 33:489–501 179. Paria BC, Chakraborty C, Dey SK 1990 Catechol estrogen formation in the mouse uterus and its role in implantation. Mol Cell Endocrinol 69:25–32 180. Liehr JG 1997 Dual role of oestrogens as hormones and pro-carcinogens: tumour initiation by metabolic activation of oestrogens. Eur J Cancer Prev 6:3–10 181. Graham JD, Clarke CL 1997 Physiological action of progesterone in target tissues. Endocr Rev 18:502–519 182. Aronica SM, Kraus WL, Katzenellenbogen BS 1994 Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription. Proc Natl Acad Sci USA 91:8517–8521 183. Curtis SW, Clark J, Myers P, Korach KS 1999 Disruption of estrogen signaling does not prevent progesterone action in the estrogen receptor knockout mouse uterus. Proc Natl Acad Sci USA 96:3646–3651 184. Das SK, Chakraborty I, Paria BC, Wang XN, Plowman G, Dey SK 1995 Amphiregulin is an implantation-specific and progesteroneregulated gene in the mouse uterus. Mol Endocrinol 9:691–705 185. Ding YQ, Bagchi MK, Bardin CW, Bagchi IC 1995 Calcitonin gene expression in the rat uterus during pregnancy. Recent Prog Horm Res 50:373–378 186. Weitlauf HM 1988 Biology of implantation. In: Knobil E, Neil JD, Ewing LL, Greenwald GS, Markert CL, Pfaff DW (eds) The Physiology of Reproduction. Raven Press, New York, pp 231–262 187. Ledford BE, Rankin JC, Markwald RR, Baggett B 1976 Biochemical and morphological changes following artificially stimulated decidualization in the mouse uterus. Biol Reprod 15:529–535 188. Stewart CL, Cullinan EB 1997 Preimplantation development of the mammalian embryo and its regulation by growth factors. Dev Genet 21:91–101 189. Lim H, Paria BC, Das SK, Dinchuk JE, Langenbach R, Trzaskos JM, Dey SK 1997 Multiple female reproductive failures in cyclooxygenase 2-deficient mice. Cell 91:197–208 190. Ma L, Benson GV, Lim H, Dey SK, Maas RL 1998 Abdominal B (AbdB) Hoxa genes: regulation in adult uterus by estrogen and progesterone and repression in Mullerian duct by the synthetic estrogen diethylstilbestrol (DES). Dev Biol 197:141–154 191. Cowell TP 1969 Implantation and development of mouse eggs transferred to the uteri of non-progestational mice. J Reprod Fertil 19:239–245 192. Galand P, Leroy F, Chretien J 1971 Effect of oestradiol on cell proliferation and histological changes in the uterus and vagina of mice. J Endocrinol 49:243–252 193. Kronenberg MS, Clark JH 1985 Changes in keratin expression during the estrogen-mediated differentiation of rat vaginal epithelium. Endocrinology 117:1480–1489 194. Gimenez-Conti IB, Lynch M, Roop D, Bhowmik S, Majeski P, Conti CJ 1994 Expression of keratins in mouse vaginal epithelium. Differentiation 56:143–151 195. Sourla A, Luo S, Labrie C, Belanger A, Labrie F 1997 Morphological changes induced by 6-month treatment of intact and ovariectomized mice with tamoxifen and the pure antiestrogen EM-800. Endocrinology 138:5605–5607 196. Luo S, Martel C, Sourla A, Gauthier S, Merand Y, Belanger A, Labrie C, Labrie F 1997 Comparative effects of 28-day treatment with the new anti-estrogen EM-800 and tamoxifen on estrogensensitive parameters in intact mice. Int J Cancer 73:381–391 197. Dukes M, Chester R, Yarwood L, Wakeling AE 1994 Effects of a non-steroidal pure antioestrogen, ZM 189,154, on oestrogen target organs of the rat including bones. J Endocrinol 141:335–341 198. Buchanan DL, Kurita T, Taylor JA, Lubahn DB, Cunha GR, Cooke PS 1998 Role of stromal and epithelial estrogen receptors in vaginal epithelial proliferation, stratification, and cornification. Endocrinology 139:4345–4352 199. Newbold RR, Bullock BC, McLachlan JA 1983 Exposure to diethylstilbestrol during pregnancy permanently alters the ovary and oviduct. Biol Reprod 28:735–744 200. Newbold RR, Bullock BC, McLachlan JA 1985 Progressive proliferative changes in the oviduct of mice following developmental exposure to diethylstilbestrol. Teratogenesis Carcinog Mutagen 5:473–480 201. Harper MJK 1988 Gamete and zygote transport. In: Knobil E, Neil JD, Ewing LL, Greenwald GS, Markert CL, Pfaff DW (eds) The Physiology of Reproduction. Raven Press, New York, pp 103–134 202. Greenwald GS 1967 Species differences in egg transport in response to exogenous estrogen. Anat Rec 157:163–72 203. Baird DT 1984 The ovary. In: Austin CR, Short RV (eds) Reproduction in Mammals: Hormonal Control of Reproduction. Cambrige University Press, Cambridge, UK, pp 91–114 204. Carr BR 1998 Disorders of the ovaries and female reproductive tract. In: Wilson JD, Foster DW, Kronenberg HM, Larsen PR (eds) Williams Textbook of Endocrinology. WB Saunders Company, Philadelphia, pp 751–817 205. Richards JS 1980 Maturation of ovarian follicles: actions and interactions of pituitary and ovarian hormones on follicular cell differentiation. Physiol Rev 60:51–89 206. Magoffin DA 1991 Regulation of differentiated functions in ovarian theca cells. Semin Reprod Endocrinol 9:321–331 207. Richards JS 1994 Hormonal control of gene expression in the ovary. Endocr Rev 15:725–751 208. Picton H, Briggs D, Gosden R 1998 The molecular basis of oocyte growth and development. Mol Cell Endocrinol 145:27–37 209. Robker RL, Richards JS 1998 Hormonal control of the cell cycle in ovarian cells: proliferation vs. differentiation. Biol Reprod 59:476– 482
Page 1 and 2: 0163-769X/99/$03.00/0 Endocrine Rev
Page 3 and 4: 360 COUSE AND KORACH Vol. 20, No. 3
Page 51: 408 COUSE AND KORACH Vol. 20, No. 3

Estrogen Receptor Null Mice - Endocrine Reviews

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?