Download presentation (PDF) - The Royal Marsden
Download presentation (PDF) - The Royal Marsden
Download presentation (PDF) - The Royal Marsden
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
<strong>The</strong> <strong>Royal</strong> <strong>Marsden</strong>c-KIT: Proof-of-concept– Initial case reports in 2008 of efficacy of c-KITtherapy in acral/mucosal melanoma– Imatinib in 3 cases / sorafenib in 1 case– All 4 patients had c-KIT alterations– This was proof-of-concept for targeted therapy inmelanomaHodi et al. J Clin Oncol. 2008 Apr 20;26(12):2046-51Lutzky et al. Pigment Cell Melanoma Res. 2008 Aug;21(4):4Kim et al. Br J Cancer. 2008 Sep 2;99(5):734-40Quintás-Cardama et al. Nat Clin Pract Oncol. 2008 Oct 21
Change language