TACKLING OBESITY IN ENGLANDAppendix 5 Thehuman costs of obesity1 Obese people are more likely to suffer from a number ofserious chronic diseases, many of which are lifelimit<strong>in</strong>g.Besides the physical effects, the psychologicaland social burdens of obesity can also be debilitat<strong>in</strong>g.Diseases associated with obesityCoronary heart disease2 The most common cause of premature mortality amongobese people is coronary heart disease. Our work onthe costs of obesity <strong>in</strong> 1998 (the latest year for whichdata were available) suggests that approximately28,000 people <strong>in</strong> <strong>England</strong> suffered a heart attack<strong>in</strong> that year that was directly attributable to obesity(Appendix 6).3 In women, obesity is the third most powerful predictorof cardiovascular disease (after age and blood pressure).This is <strong>in</strong> part because it is strongly associated with otherimportant risk factors for heart disease such as highblood pressure and high cholesterol. The risk of heartattack for an obese woman is approximately three timesthat of a lean woman of the same age 44 .Osteoarthritis6 Osteoarthritis, or degenerative disease of the weightbear<strong>in</strong>gjo<strong>in</strong>ts such as the knee, is a very commoncomplication of obesity, which causes a great deal ofdisability 47 . Pa<strong>in</strong> <strong>in</strong> the lower back is also frequentlysuffered by obese people, and may be one of the majorcontributors to obesity-related absences from work. It islikely that the excess weight alone, rather than anymetabolic affect, is the cause of these problems.Respiratory disease7 Many respiratory disorders are related to obesity, themost serious of which is obstructive sleep apnoea.Sufferers experience the <strong>in</strong>termittent cessation ofbreath<strong>in</strong>g dur<strong>in</strong>g sleep, which causes broken sleeppatterns and may contribute to high blood pressure andheart disease 48 .Reproductive disorders8 Obese people of both sexes are more likely to sufferreproductive disorders, and for obese women there is an<strong>in</strong>creased risk of complications dur<strong>in</strong>g pregnancy. 49Type 2 diabetes4 Of all serious diseases, Type 2 diabetes has the strongestassociation with obesity 10 . The metabolic problemswhich give rise to this type of diabetes most commonlyoccur as a result of excess weight. Indeed, the risk ofdevelop<strong>in</strong>g Type 2 diabetes rises with <strong>in</strong>creas<strong>in</strong>g bodymass <strong>in</strong>dex well below the threshold of cl<strong>in</strong>ical obesity.Women who are obese are 12 times more likely todevelop non-<strong>in</strong>sul<strong>in</strong> dependent diabetes than women ofa healthy weight. Diabetes itself predisposes people tohigh blood pressure and heart disease 45 .Cancer5 The l<strong>in</strong>k between obesity and cancer is less welldef<strong>in</strong>ed.Research suggests that the risk of a number ofcancers is <strong>in</strong>creased by obesity, <strong>in</strong>clud<strong>in</strong>g: breast cancerand cancer of the endometrium, uterus, cervix, ovaryand gall-bladder <strong>in</strong> women; and cancer of the rectumand prostate <strong>in</strong> men 46 . The clearest association is withcancer of the colon, for which obesity <strong>in</strong>creases the riskby nearly three times <strong>in</strong> both men and women.Social and psychological penaltiesStigmatisation9 In studies that have exam<strong>in</strong>ed the reactions ofschoolchildren to various forms of physical disabilityand obesity, obese children were consistently rated theleast attractive by their peers. In one study of obeseschoolgirls, obesity was rated a social stigma by78 per cent of girls <strong>in</strong> the healthy weight range, and62 per cent of overweight girls 50 . Obese girls wereperceived by their peers to be less active, less attractive,less healthy, weak-willed and hav<strong>in</strong>g <strong>in</strong>ferior physicalabilities and poor self-control regard<strong>in</strong>g dietary habits.10 Another study noted that <strong>in</strong> affluent societies, obesepeople are subject to <strong>in</strong>tense prejudice anddiscrim<strong>in</strong>ation, and that children as young as sixdescribe obese children as "lazy, dirty, stupid, ugly,cheats and liars" 51 . Thus, the stigma of overweightappears to have two aspects: stigmatisation of theappearance of the body and stigmatisation of thecharacter of the person for the perceived moral failure ofnot controll<strong>in</strong>g one's weight.appendix five55
TACKLING OBESITY IN ENGLANDImpact on mental health11 Obese people, and the severely obese <strong>in</strong> particular, aremore likely to suffer from a number of psychologicalproblems, <strong>in</strong>clud<strong>in</strong>g b<strong>in</strong>ge-eat<strong>in</strong>g, low self-image andconfidence, and a sense of isolation and humiliationaris<strong>in</strong>g from practical problems 10 .12 In a study that exam<strong>in</strong>ed the psychological wellbe<strong>in</strong>g ofextremely obese patients await<strong>in</strong>g surgery to <strong>in</strong>duceweight loss, many more patients listed social rather thanmedical considerations as their ma<strong>in</strong> reason for seek<strong>in</strong>gsurgery. Of these patients, 40 per cent said they "always"or "usually" had experienced acts of discrim<strong>in</strong>ation atwork, with<strong>in</strong> the family or <strong>in</strong> a public place; 77 per centfelt depressed and <strong>in</strong> low spirits daily or almost daily;and all patients considered themselves unattractive.13 It is difficult to separate cause from effect <strong>in</strong> therelationship between obesity and psychologicaldisorders. Whilst mental wellbe<strong>in</strong>g may suffer as a resultof the pressures associated with be<strong>in</strong>g obese,psychological problems may equally contribute to thetype of behaviours, such as emotional and b<strong>in</strong>ge-eat<strong>in</strong>g,that can result <strong>in</strong> the onset of obesity.appendix five56